Results 21 to 30 of about 1,301,382 (246)

Optimization of Baseplate Hub Design for Swaging Operation

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
Swaging process is studied through a 2-D axisymmetric finite element model with non-linear material models and allowing large deformation. The effects of major baseplate hub geometrical parameters are studied for the case of a single actuator arm with ...
K.C. EE, Peter HAHN, Brett HOLAWAY
doaj   +1 more source

Profiling Thermus thermophilus Argonaute Guide DNA Sequence Preferences by Functional Screening

open access: yesFrontiers in Molecular Biosciences, 2021
Prokaryotic Argonautes (pAgo) are an increasingly well-studied class of guided endonucleases, and the underlying mechanisms by which pAgo generate nucleic acid guides in vivo remains an important topic of investigation.
Eric A. Hunt   +4 more
doaj   +1 more source

Strategies for new product development [PDF]

open access: yesBusiness Horizons, 1972
Abstract In spite of much evidence of its success, many managers hesitate to establish a policy for new product development. Their indecision often arises from two reasons: they fear that a defined strategy may discourage innovation and they are uncertain how to formulate a new product strategy. The author of this article discredits the former notion
openaire   +2 more sources

Metabolomic and quality data for early and late passages of an antibody-producing industrial CHO cell line

open access: yesData in Brief, 2020
In this article, we provide four data sets for an industrial Chinese Hamster Ovary (CHO) cell line producing antibodies during a 14-day bioreactor run. This cell line was selected for further evaluation because of its significant titer loss as the cells ...
Steven W. Sowa   +13 more
doaj   +1 more source

Mycobacterium indicus pranii Induced Memory T-Cells in Lung Airways Are Sentinels for Improved Protection Against M.tb Infection

open access: yesFrontiers in Immunology, 2019
The lungs are the most vulnerable site for air-borne infections. Immunologic compartmentalization of the lungs into airway lumen and interstitium has paved the way to determine the immune status of the site of pathogen entry, which is crucial for the ...
Ananya Gupta   +6 more
doaj   +1 more source

A literature review of liver function test elevations in rifampin drug–drug interaction studies

open access: yesClinical and Translational Science, 2022
Although rifampin drug–drug interaction (DDI) studies are routinely conducted, there have been instances of liver function test (LFT) elevations, warranting further evaluation.
Sherry M. Ibrahim   +3 more
doaj   +1 more source

Microstructural Engineering of Cathode Materials for Advanced Zinc‐Ion Aqueous Batteries

open access: yesAdvanced Science, 2021
Zinc‐ion batteries (ZIBs) have attracted intensive attention due to the low cost, high safety, and abundant resources. However, up to date, challenges still exist in searching for cathode materials with high working potential, excellent electrochemical ...
Mei Er Pam   +11 more
doaj   +1 more source

A novel immunodeficient NOD.SCID-rd1 mouse model of retinitis pigmentosa to investigate potential therapeutics and pathogenesis of retinal degeneration

open access: yesBiology Open, 2017
Retinitis pigmentosa (RP) is a common retinal degeneration disease caused by mutation in any gene of the photo transduction cascade and results in photoreceptor dystrophy.
Alaknanda Mishra   +13 more
doaj   +1 more source

Enhanced survival of BCG-stimulated dendritic cells: involvement of anti-apoptotic proteins and NF-κB

open access: yesBiology Open, 2018
BCG (Bacillus Calmette-Guérin) is the only available vaccine against TB and is also used for the treatment of superficial bladder cancer. BCG-mediated protection against TB and bladder cancer has been shown to rely on its ability to induce superior CD4 ...
Pawan Kumar   +3 more
doaj   +1 more source

New Product Development [PDF]

open access: yesNew England Journal of Entrepreneurship, 2000
NEJE Editors interview Steve Kaye, CEO of Steve Kaye New Products, Inc.
Steve Kaye
doaj   +1 more source

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