Results 21 to 30 of about 5,313,232 (289)

Enhanced survival of BCG-stimulated dendritic cells: involvement of anti-apoptotic proteins and NF-κB

Biology Open, 2018
BCG (Bacillus Calmette-Guérin) is the only available vaccine against TB and is also used for the treatment of superficial bladder cancer. BCG-mediated protection against TB and bladder cancer has been shown to rely on its ability to induce superior CD4 ...
Pawan Kumar, Vini John, Ananya Gupta, Sangeeta Bhaskar   +3 more
doaj   +1 more source

New Product Development [PDF]

New England Journal of Entrepreneurship, 2000
NEJE Editors interview Steve Kaye, CEO of Steve Kaye New Products, Inc.
Steve Kaye
doaj   +1 more source

Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics

mAbs, 2020
Manufacturability of immunoglobulin G4 (IgG4) antibodies from the Chemistry, Manufacture, and Controls (CMC) perspective has received little attention during early drug discovery.
Zhiqiang Chen, Yueming Qian, Yuanli Song, Xuankuo Xu, Li Tao, Nesredin Mussa, Sanchayita Ghose, Zheng Jian Li   +7 more
doaj   +1 more source

Snail: An Eco-Friendly Autonomous Steam Mopping Robot for Cleaning and Disinfection of Floors

Mathematics, 2023
Steam mopping is an eco-friendly solution for cleaning and disinfecting floors, avoiding harsh chemicals or harmful UV lights. Currently, commercial steam mopping systems are manually operated, which is laborious and unsafe. This work presents the design
Sathian Pookkuttath, Mohan Rajesh Elara, Madan Mohan Rayguru, Zaki Saptari Saldi, Vinu Sivanantham, Balakrishnan Ramalingam   +5 more
doaj   +1 more source

Testing goodwill: Conflict and co-operation in new product development networks [PDF]

, 2003
Network forms are often seen as models of organisational flexibility, promoting the building of trust and exchange of information between different business functions while offering both cost savings and reductions in the uncertainties usually associated
Coles, AM, Dickson, K, Harris, L
core   +1 more source

Treatment With Tafamidis Slows Disease Progression in Early-Stage Transthyretin Cardiomyopathy

Clinical Medicine Insights: Cardiology, 2017
Background: Transthyretin cardiomyopathy (TTR-CM) is a progressive, fatal disease caused by the accumulation of misfolded transthyretin (TTR) amyloid fibrils in the heart.
Marla B Sultan, Balarama Gundapaneni, Jennifer Schumacher, Jeffrey H Schwartz   +3 more
doaj   +1 more source

A conceptual model for finding key factors for new product development evaluation

Journal of Innovation Management, 2021
This paper develops a conceptual model for finding key factors for new product development (NPD) evaluation. It builds on the work of the most cited and published authors on innovation management, but transfers attention from advertising aspects and ...
Rhys Williams, Pouya S. Moghadam, John Mulyata   +2 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration

mAbs
The bispecific antibody tarperprumig (ALXN1820) was developed as a treatment option for diseases involving dysregulated complement alternative pathway (AP) activity that could be administered in small volumes, either subcutaneously or intravenously ...
Paul Tamburini, Dennis Vestergaard Pedersen, Denise Devore, Josh Cone, Rekha Patel, Todd Hunter, Fang Sun, Gregers Rom Andersen, Jeffrey Hunter   +8 more
doaj   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source