Results 51 to 60 of about 5,313,232 (289)
The performance of a 100 kW proton exchange membrane fuel cell designed for truck applications
Next EnergyFuel cell electric vehicles offer a potential solution for achieving the objectives of the energy transition currently underway, which entails replacing combustion vehicles with vehicles that are low in environmental impact. Thus, this market is expected
Aakash Collin +3 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Mainstay chemotherapy for malaria is often faced with the problem of instability and poor bio-distribution thus resulting in impaired pharmacokinetics. Nanomedicine has been acclaimed for its success in drug delivery and improved efficacy. The aim of the
Oyetunde Oyeyemi +7 more
doaj +1 more source
mAbs, 2020 Disulfide bonds play a crucial role in folding and structural stabilization of monoclonal antibodies (mAbs). Disulfide bond reduction may happen during the mAb manufacturing process, resulting in low molecular weight species and possible failure to meet ...
Peifeng Tang +11 more
doaj +1 more source
Degradation analysis of tribologically loaded carbon nanotubes and carbon onions
npj Materials Degradation, 2023 Coating laser-patterned stainless-steel surfaces with carbon nanotubes (CNT) or carbon onions (CO) forms a tribological system that provides effective solid lubrication.
T. MacLucas +8 more
doaj +1 more source
Integrating R&D and marketing in new product development [PDF]
, 2011 R&D - marketing integration is considered to be a critical activity within New Product Development (NPD). A theoretical framework for the study of R&D - marketing integration levels developed by Gupta et al (1986) is one of the most widely cited R&D ...
Duhovnik, Joze +2 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
SMEs and virtual R&D teams: a motive channel for relationship between SMEs [PDF]
, 2009 In today?s dynamic marketplace, manufacturing companies are under strong pressure to introduce new products for long-term survival with their competitors.
Ahmed, S. +2 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Design Opportunities in Service-Product Combined Systems [PDF]
, 2009 This paper aims to examine recent research issues related to the integration of service and product in view of industrial design. Further, it attempts to identify new opportunities for further research regarding “product-servicization” vs.
Jung, Mi-Jin, Nam, Ki-Young
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source