Results 271 to 280 of about 28,373,227 (361)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Eradication of commercial tobacco related disease and death. [PDF]

Tob Control
Maddox R, Telford RM, Waa A, Diaz A, Bradbrook SK, Calma T, Whop LJ.   +6 more
europepmc   +1 more source

Incorporating New Generation Cold-Formed High-Strength Steel (CFHSS) to the Conformity of Present Product Standards

Cher Siang Tan, Philip Chie Hui Ling, Jian Jun Moy   +2 more
openalex   +1 more source

Estimating the Benefits of New Products [PDF]

, 2019
Diewert, Erwin, Feenstra, Robert C
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Marketing for Sensa: a 'zero nicotine vapor product' from a major tobacco company. [PDF]

Tob Control
Robichaud MO, Talbot EM, Ganz O, Mercincavage M, Erythropel HC, Zimmerman JB, Jabba SV, Jordt SE, Delnevo CD.   +8 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Global health burdens of plastics: a lifecycle assessment model from 2016 to 2040.

Lancet Planet Health
Deeney M, Hamelin L, Vialle C, Yan X, Green R, Yates J, Kadiyala S.   +6 more
europepmc   +1 more source

Development of functional meat products based on the food safety system. [PDF]

Sci Rep
Serikkyzy M, Kapysheva U, Kenenbay S.
europepmc   +1 more source