Results 121 to 130 of about 3,559,907 (314)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
RESCUING PUBLICNESS FROM ORGANIZATION STUDIES [PDF]
Does publicness still make sense as an issue for further research? Classic organizational sociology (or standard theory) has provided a breakthrough for understanding public administration and management, but has not fully explored the agenda. Publicness
Jean-Claude Thoenig
core
Managerialism and the neoliberal university: Prospects for new forms of "open management" in higher education [PDF]
, 2013 The restructuring of state education systems in many OECD countries during the last two decades has involved a significant shift away from an emphasis on administration and policy to an emphasis on management.
Peters, Michael A.
core +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Virtual organization delivering public services [PDF]
, 2006 In the last decades of twentieth century, the subject of the administrative reform started to be in the agenda of great part of the governments of the industrialized countries.
Rodrigues, Miguel
core
FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
Efficiency considerations and the allocation of new deal funds: an examination of the public goods explanation of expenditure patterns [PDF]
The uneven state-level distribution of New Deal spending has been frequently studied and a variety of economic and political models have been developed.
David L. Black +2 more
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Rail Passenger Selective Screening Summit, MTI S-09-01 [PDF]
, 2009 This publication is an edited transcript of the Rail Passenger Selective Screening Summit, which was co-sponsored by MTI and the American Public Transportation Association (APTA) in Chicago, Illinois on June 18, 2009, during APTA´s annual Rail Conference.
MTI
core +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Change Management as a Critical Success Factor in e-Government Implementation [PDF]
Change management in e-government implementation is a very complex issue. E-government services are frequently distributed over different IT systems and organizations.
Janja Nograšek
core +1 more source