Results 81 to 90 of about 2,164,175 (301)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Imaging Diagnosis of Urethral Leiomyoma, usual Tumour at an Unusual Location [PDF]

Journal of Clinical and Diagnostic Research, 2014
Leiomyomas are benign tumours of smooth muscle origin and are the most common uterine masses in females of reproductive age group. Extrauterine leiomyomas are also encountered occassionally and most commonly they involve the genitourinary tract ...
Ritu Verma, Shibani Mehra, U.C.Garga, Nishchint Jain, Krishna Bhardwaj   +4 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Multiple shock structures in a radio selected cluster of galaxies

, 2011
We present a new radio-selected cluster of galaxies, 0217+70, using observations from the Very Large Array and archival optical and X-ray data. The new cluster is one of only seven known that has candidate double peripheral radio relics, and the second ...
Brown, Brown, Cassano, Deiss, Liang, Markevitch, Miniati, Norris, Ponman, Rottgering, Rudnick, Ryu, Skillman, Voges   +13 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

QUASAT: An orbiting very long baseline interferometer program using large space antenna systems [PDF]

, 1985
QUASAT, which stands for QUASAR SATELLITE, is the name given to a new mission being studied by NASA. The QUASAT mission concept involves a free flying Earth orbiting large radio telescope, which will observe astronomical radio sources simultaneously with
Freeland, R. E., Jordan, J. F., Levy, G. S., Potts, D. L.   +3 more
core   +1 more source

Cosmic rays and Radio Halos in galaxy clusters : new constraints from radio observations

, 2007
Clusters of galaxies are sites of acceleration of charged particles and sources of non-thermal radiation. We report on new constraints on the population of cosmic rays in the Intra Cluster Medium (ICM) obtained via radio observations of a fairly large ...
D. Dallacasa, Dolag K., Feretti L., G. Brunetti, G. Setti, K. Dolag, R. Cassano, Reimer O., S. Giacintucci, Subramanian K., T. Venturi   +10 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Optical and radio properties of giant radio quasars: Central black hole characteristics

, 2012
We analysed the optical and radio properties of lobe-dominated giant-sized (> 0.72 Mpc) radio quasars and compared the results with those derived for a sample of smaller radio sources to determine whether the large size of some extragalactic radio ...
Jamrozy, M., Kuźmicz, A.
core   +1 more source