Results 121 to 130 of about 1,438,279 (284)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Journal of the New York Botanical Garden
, 1947 Vols. for 1933-1941, 1945 include the Annual report of the director, 1933-1940, 1944 (previously published in its Bulletin). Indexes: Vols. 1-15, 1900-1914, issued as v. 15, no. 180; Vols. 16-30, 1915-1929, issued as v. 30, no. 360.
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Journal of the New York Botanical Garden
, 1949 Vols. for 1933-1941, 1945 include the Annual report of the director, 1933-1940, 1944 (previously published in its Bulletin). Indexes: Vols. 1-15, 1900-1914, issued as v. 15, no. 180; Vols. 16-30, 1915-1929, issued as v. 30, no. 360.
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New Jersey Clean Air Council Meeting Record
, 2020 Two presentations, but no minutes included: Comparison of 2020 Nitrogen Oxides and Fine Particle Concentration on New Jersey with Data from 2014-2019 & The Impact of the "Stay at Home" Directive in the Air Quality in New ...
New Jersey Clean Air Council
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FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Journal of the New York Botanical Garden
, 1937 Vols. for 1933-1941, 1945 include the Annual report of the director, 1933-1940, 1944 (previously published in its Bulletin). Indexes: Vols. 1-15, 1900-1914, issued as v. 15, no. 180; Vols. 16-30, 1915-1929, issued as v. 30, no. 360.
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Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source