Results 81 to 90 of about 22,062,635 (277)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The Buchtel Record, Vol. 3, No. 1
, 2020 The Buchtel Record is the first student-operated newspaper and literary magazine of Buchtel College. Published from 1882-1884, the newspaper covers campus and community news, including sections such as opinions, arts, and local advertisements.
Buchtel Record
core
The Buchtel Record, Vol. 2, No. 1
, 2020 The Buchtel Record is the first student-operated newspaper and literary magazine of Buchtel College. Published from 1882-1884, the newspaper covers campus and community news, including sections such as opinions, arts, and local advertisements.
Buchtel Record
core +1 more source
European Journal of TaxonomyThe Chinese species of the genus Phanerotoma (Hymenoptera, Braconidae, Cheloninae) are revised. In total, 44 species are recognised, of which 24 are newly described: P. acclivirugata sp. nov., P. acuticlypealis sp. nov., P. aequidentata sp.
Wen-Juan Luo +4 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The Buchtel Record, Vol. 3, No. 2
, 2020 The Buchtel Record is the first student-operated newspaper and literary magazine of Buchtel College. Published from 1882-1884, the newspaper covers campus and community news, including sections such as opinions, arts, and local advertisements.
Buchtel Record
core +1 more source
Journal of Crop Protection, 2017 Twelve species of the genus Aphelenchoides were collected and identified based on morphological and morphometric characters from different regions in North, South and Western Iran. Among collected species i. e. A. centralis, A. cibolensis, A.
Yaser Adeldoost +3 more
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source