Results 71 to 80 of about 3,923,667 (328)

Bayesian Non-Exhaustive Classification A Case Study: Online Name Disambiguation using Temporal Record Streams [PDF]

, 2016
The name entity disambiguation task aims to partition the records of multiple real-life persons so that each partition contains records pertaining to a unique person. Most of the existing solutions for this task operate in a batch mode, where all records
Bunescu R., Chen P.-Y., Davis A., de Carvalho A. P., Dundar M., Lee D. D., Michaud D. J., Sethuraman J., Zhang B.   +8 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Antóceros e hepáticas dos Estados de Alagoas, Bahia, Pernambuco e Sergipe, Brasil, depositados no Herbário SP

Hoehnea
Durante o estudo de antóceros e hepáticas depositados no herbário Maria Eneyda P. Kauffmann Fidalgo (SP) foram identificados 197 táxons de Anthocerotophyta e Marchantiophyta para os Estados de Alagoas, Bahia, Pernambuco e Sergipe.
Olga Yano, Denilson Fernandes Peralta, Juçara Bordin   +2 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

New genera and species of scuttle flies (Diptera, Phoridae) from Cameroon [PDF]

Journal of Insect Biodiversity and Systematics
Despite the ongoing challenges in identifying Afrotropical Phoridae, this study contributes significantly to the understanding of the scuttle flies (Diptera: Phoridae) from Cameroon.
Ronald Henry Lambert Disney
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Novas ocorrências de briófitas nos estados brasileiros

Hoehnea
São citadas 79 espécies distribuídas em 65 gêneros e 38 famílias, sendo que 53 espécies são novas ocorrências e 26 tiveram a distribuição geográfica ampliada para os Estados de Ceará, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Paraná, Rio de ...
Denilson Fernandes Peralta, Juçara Bordin, Olga Yano   +2 more
doaj   +1 more source

Das Höhlenlangbein Amilenus aurantiacus (Opiliones: Phalangiidae) ist Höhlentier des Jahres 2016 in Deutschland

Arachnologische Mitteilungen, 2016
With the nomination of the ‘Cave Animal of the Year’ the Society of German Cave and Karst Explorers calls public and authorities’ attention to the understudied biodiversity of subterranean ecosystems.
Zaenker, Stefan, Schönhofer, Axel L., Blick, Theo   +2 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A new genus of the millipede tribe Brachyiulini (Diplopoda: Julida: Julidae) from the Aegean region

European Journal of Taxonomy, 2013
A new genus of the julid tribe Brachyiulini, Enghophyllum gen. nov., is described, comprising two species from Greece. The type-species, E. naxium (Verhoeff, 1901) comb. nov. (ex Megaphyllum Verhoeff, 1894), appears to be rather widespread in the Aegean:
Eszter Lazányi, Boyan Vagalinski
doaj   +1 more source