Results 61 to 70 of about 18,854,879 (265)

Die Bedeutung der zeitgenössischen Architektur für die Regionen und die Regionalentwicklung im Alpenraum

open access: yesArchAlp, 2020
"The Alps are characterised by a plethora of little regions that all developed very different building styles before the advent of the Industrial Age. Nature, culture, and history all contributed to modifying them over time.
Werner Bätzing
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Competitiveness and sustainability: can ‘smart city regionalism’ square the circle? [PDF]

open access: yes, 2013
Increasingly, the widely established, globalisation-driven agenda of economic competitiveness meets a growing concern with sustainability. Yet, the practical and conceptual co-existence—or fusion—of these two agendas is not always easy.
Herrschel, T., Tassilo Herrschel
core   +1 more source

Nature and the city: changes for the first urban Century in the United States [PDF]

open access: yesCiudades, 2009
This panoramic view shows how are focused today the relationships between Nature and the City by research scholars and practitioners in North America. In the American context of an “endless city”, it develops four key ideas for a better approach to urban
Frederick R. Steiner
doaj  

Integration Dilemmas of the Common Economic Space

open access: yesVestnik MGIMO-Universiteta, 2012
The paper addresses key political economy dilemmas associated with the formation of the Common Economic Space (CES) by Russia, Belarus, and Kazakhstan.
S. A. Afontsev
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Asian Economic Integration and Cooperation: Challenges and Ways Forward for Pan-Asian Regionalism [PDF]

open access: yes
As the Asian economies have grown larger and become more complex, they have also be-come more integrated at both the regional and the subregional level. Yet although economic integration has increased, regionalism in the sense of economic cooperation at ...
Durgesh K. Rai
core  

Home - About - Disclaimer - Privacy