Results 241 to 250 of about 39,038,474 (368)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Wireless sensors network based physiological parameters monitoring system : a project report [i.e. thesis] submitted in partial fulfilment of the requirements for the degree of Master of Engineering in Electronics and Telecommunication Engineering, School of Engineering and Advanced Technology, Massey University, Palmerston North, New Zealand

, 2010
Karandeep Malhi
openalex   +1 more source

New Delhi Metallo-β-Lactamase (NDM-1)-Producing Klebsiella pneumoniae: Case Report and Laboratory Detection Strategies [PDF]

, 2011
A. Brian Mochon, Omai B. Garner, Janet A. Hindler, Paul Krogstad, Kevin W. Ward, Michael A. Lewinski, J. Kamile Rasheed, Karen Anderson, Brandi Limbago, Romney M. Humphries   +9 more
openalex   +1 more source

International consensus report on the investigation and management of primary immune thrombocytopenia.

Blood, 2010
D. Provan, R. Stasi, A. Newland, V. Blanchette, P. Bolton-Maggs, J. Bussel, B. Chong, D. Cines, T. Gernsheimer, B. Godeau, J. Grainger, I. Greer, B. Hunt, P. Imbach, G. Lyons, R. Mcmillan, F. Rodeghiero, M. Sanz, M. Tarantino, S. Watson, Joan Young, D. Kuter   +21 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A New Report of Nezara viridula f. aurantiaca (Heteroptera: Pentatomidae) from a Cultured Population in Washington County, Mississippi. [PDF]

J Insect Sci, 2017
Rojas MG, Morales-Ramos JA.
europepmc   +1 more source

Health hazard evaluation report: HETA-81-314-1435, Rutgers University, Newark, New Jersey.

, 1984
P Ebbessen>, M Doenhoff, E Allen>, W Gardner, 0 Smith, R Prentice, D Thompson, W Herrmann, H Ziel, W Finkle>, T Mack, M Pike, B Henderson, R Pfeffer, V Gerkins, M Arthur, S Brown, J Halitsky, J Halitsky, P Lagus   +19 more
openalex   +1 more source

Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report

Gut, 2016
P. Malfertheiner, F. Mégraud, C. O'Morain, J. Gisbert, E. Kuipers, A. Axon, F. Bazzoli, A. Gasbarrini, J. Atherton, D. Y. Graham, R. Hunt, P. Moayyedi, T. Rokkas, M. Rugge, M. Selgrad, S. Suerbaum, K. Sugano, E. El-Omar   +17 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source