Results 111 to 120 of about 1,373,520 (306)

New social movements re-enchant the world [PDF]

, 2017
El artículo propone revisar los análisis convencionales sobre los nuevos movimientos sociales con la propuesta de que es necesario incorporar la dimensión afectiva o de adhesión emocional, sin la que, a nuestro juicio, difícilmente puede comprenderse
Hernández Ramírez, Javier, Talego Vázquez, Félix   +1 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The New Generation of Community Foundations [PDF]

, 2012
Community foundations have enjoyed considerable growth in recent years, not only in their number but also in their character. This emergence of a "new generation" of community foundations is occurring within a larger context of other emerging forms of ...
Alison Mathie, Barry Knight, Jenny Hodgson   +2 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Environmental education and new social movements: contributions to educational change [PDF]

, 2010
[Resumo] O artigoexplora o vínculo entre educación ambiental e cambio educativo desde a perspectiva da comunidade discursiva da política cultural. Esta línea discursiva constrúese a partir de accións promovidas polos novos movementos sociais, como o ...
Rodríguez Romero, María Mar, Serantes-Pazos, Araceli   +1 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Inovações sociais e governança regional no Quebec: que lugar resta aos novos movimentos sociais?

Ciências Sociais Unisinos, 2011
Social movements have been important sources of change and social innovation in Québec, at the national level but also in each of its regions where they were imbedded.
Denyse Côté, Étienne Simard
doaj  

Mature Cooperative Groups Seeking New Identities: The Case of Belgium [PDF]

The cooperative sector in Belgium has always been very much linked to other social movements. In the 1990s the backbone of the sector, namely the cooperative banks, have undergone major transformations. In this article, the two most important cooperative
Develtere, Patrick, Raymaekers, Peter
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source