Results 111 to 120 of about 178,222 (302)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Popular education methodology, activist academics and emergent social movements: Agents for environmental justice (Action Note)

open access: yes, 2019
University-based activists constantly find themselves at an interface between the institution that employs them and the social movements to which they are committed.
Scandrett, Eurig
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Editorial: Feminism, women’s movements and women in movement

open access: yes, 2011
Introduction to Special Issue that engages with the increasingly important, separate yet interrelated themes of feminism, women’s movements and women in movement in the context of global ...
Flesher Fominaya, Christina   +3 more
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Occupy Democracy: A Study of New Media Use by a Sub-branch of the Occupy London Movement [PDF]

open access: yes, 2015
The rise of new media through network globalisation has led to innovative forms of “new” social movements. This study will explore whether Occupy London, a branch of the global Occupy movement, fits within the realm of a “new” social movement.
Petrosian, Vardan
core  

Democratisation and New Social Movements

open access: yes, 2017
The article offers a reflection on the processes of democratisation in Slovenia, arguing that the new social movements were a key player in initiating and directing democratic transformation, but later came to be gradually marginalised with the ...
Žiga Vodovnik
core   +1 more source

Solidarity as a New Social Movement

open access: yesPolitical Science Quarterly, 1989
Poland's Solidarity was one of the largest social movements in history. For sixteen months following its birth in the workers' strikes in the summer of 1980, it dramatically altered the face and teinper of Poland. Because of its size and popularity, it threatened the very foundations of communist rule in Poland.
openaire   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

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