A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Positive, Neutral, or Just Normal? A Focus Group Study on Adolescents' Knowledge, Familiarity and Perceived Effectiveness of Body Positivity and Body Neutrality on Social Media. [PDF]
Ouvrein G, Schreurs L.
europepmc +1 more source
Social Media and New Protest Movements [PDF]
Poell, T., van Dijck, J.
openaire +2 more sources
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Globalization, social movements and the new internationalisms
This text reinterprets the history of labour internationalism. It examines the old internationalism of labour and socialism, and the present one of the new radical-democratic social movements, such as that of women and feminism.
Waterman, Peter 1936-
core
Ethics and action pathways for psychologists in a time of climate crisis. [PDF]
Houlding C +5 more
europepmc +1 more source
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Digital Discourse, Secondary Victimization, and Psychological Harm: Mixed-Methods Analysis of System Justification in the #MeToo Movement. [PDF]
Parekh H, Thakkar S, Bhatt P, Akello P.
europepmc +1 more source
REPUBLICANISM AND POSTMODERNISM IN NEW SOCIAL MOVEMENTS An approach to the indignados movement
This paper explores some theoretical links between contemporary republicanism and social movements, with a postmodern approach, in a search forgreater participation, democratic regeneration and political innovation through the centrality of public spaces as a political locus.
openaire +2 more sources
Dementia Incidence in Individuals With Parkinson's Disease in the Framingham Heart Study
ABSTRACT Limited information exists on incident dementia in individuals with Parkinson's disease (PD) in US community‐based samples. We examined cognitive statuses and PD diagnoses of 183 individuals in the Framingham Heart Study (FHS) to establish incident dementia, mortality rates, associations with sex, age at PD onset, and education level.
Joshi Dookhy +11 more
wiley +1 more source

