Results 51 to 60 of about 1,374,901 (307)

Teoria crítica e os sentidos da emancipação

open access: yesCaderno CRH
A tradição de pensamento conhecida como Teoria Crítica, que conta com os nomes de Horkheimer, Adorno, Marcuse e Habermas, entre muitos outros, é composta por diferentes modelos críticos.
Rúrion Melo
doaj   +1 more source

[Review of] Juan Flores. Divided Borders: Essays all Puerto Rican Identity [PDF]

open access: yes, 1994
Juan Flores makes an important contribution to the literature on the Puerto Rican experience with his new book, Divided Borders: Essays all Puerto Rican Identity.
Reyes, Migdalia
core   +1 more source

Injertarse en la Historia. Gesto creativo y estrategias de reapropiación en el activismo global. [PDF]

open access: yes, 2013
Resumen: Este trabajo trata de desentrañar los modos en que los actuales movimientos sociales impulsan un proceso de reapropiación que se extiende en diversos ámbitos.
González Marí, Ximo
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

La crisis social de la política y la movilización política de la crisis: el 15-M

open access: yesMélanges de la Casa de Velázquez, 2017
This article sets out to rethink the relation between mobilisation and democratisation processes in Spain since the inception of the 15M movement. More specifically, we propose to analyse: 1) the origin of the movement, sparked by the social consequences
Benjamín Tejerina, Ignacia Perugorría
doaj   +1 more source

Stepping out of the ivory tower:a sociological engagement in ‘the cult wars’ [PDF]

open access: yes, 2016
The paper describes how the author‟s research into a new religious movement in the 1970s led to her finding herself a player in the „cult wars‟, with a variety of different groups competing to have their constructions of images of the movements accepted ...
Barker, Eileen
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Social Movements Facing the Processes of Globalization: Beyond the Paradigms of Class and Identity [PDF]

open access: yes, 2004
This essay focuses on a particular expression of globalization and regionalization that entails social, political, cultural and economic dimensions: social movements.
Alfaro, Verónica
core   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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