Results 91 to 100 of about 25,011,453 (356)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

a space in a space in a space

open access: yes, 2022
Fisher was invited by Head of Visual Arts Programming, Neil Walker to develop a new body of work for a solo exhibition, 'a space in a space in a space' at Angear Gallery, Lakeside Arts Centre, University of Nottingham, Nottingham 7 May - 26 June 2022 ...
Fisher, C.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modular and Highly Reliable COTS-Based Power Conditioning and Distribution Unit for Small Satellites

open access: yesAerospace
This paper presents a modular Power Conditioning and Distribution Unit (PCDU) designed for small satellites. The proposed system features a highly adaptable architecture capable of managing a total power throughput of up to 100 W, with specific limits ...
Cristian Torres Vergara   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Space is the machine: a configurational theory of architecture

open access: yes, 2007
Since The social logic of space was published in 1984, Bill Hillier and his colleagues at University College London have been conducting research on how space features in the form and functioning of buildings and cities. A key outcome is the concept of â€
Hillier, B, Hillier, Bill
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

New Jersey open space policy plan

open access: yes, 1967
PREFACE iii; THE GOVERNOR'S INTERDEPARTMENTAL COMMITTEE FOR STATE PLANNING iv; OPEN SPACE SUBCOMMITTEE OF THE GOVERNOR'S INTERDEPARTMENTAL COMMITTEE FOR STATE PLANNING vi; SUMMARY 1; I THE CHALLENGES AND ISSUES OF OPEN SPACE PLANNING 5; II ...
New Jersey. Division of State and Regional Planning. Bureau of Statewide Planning.
core  

Open Space Plan Requirements

open access: yes, 2001
The New Jersey Meadowlands Commission (NJMC) has prepared this list of open space standards and requirements with an open space requirement chart and a tree planting table.

core   +1 more source

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