Results 131 to 140 of about 23,552,421 (303)

Beyond new space: Changing organizational forms, collaborative innovation and public and semi-public domains

The core argument of this paper is that a new stage of a rather complex co-existence and co-evolution of space organizations is being entered with the emergence of public-private collaborative organizations driven by digitalization, sustainability and ...
Cunha, MPE, Clegg, S, Heitor, M, Sirage, E, Oliveira, P   +4 more
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The challenges in drafting national law for space activities: A Brazilian experience

, 2014
The international space law regime mandates that individual nation states are both responsible and liable for their respective national space activities. This is one of the most important norms of space law, which face today more than never the challenge
RIBEIRO VIANA, TATIANA
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Smile-shaped electron gradient distributions observed during magnetic reconnection at Earth’s magnetopause

Communications Physics
The electron diffusion region is central to NASA’s Magnetospheric Multiscale (MMS) mission to understand collisionless magnetic reconnection, the plasma physics phenomenon crucial to triggering the explosive energy release of solar flares, powering ...
Jason R. Shuster, Naoki Bessho, John C. Dorelli, Daniel J. Gershman, Jason M. H. Beedle, Harsha Gurram, Jonathan Ng, Li-Jen Chen, Roy B. Torbert, James L. Burch, Barbara L. Giles, Richard E. Denton, Paul A. Cassak, M. Hasan Barbhuiya, Steven J. Schwartz, Yi-Hsin Liu, Cecilia Norgren, Daniel E. da Silva, Kevin J. Genestreti, Steven V. Heuer, Matthew R. Argall, Hanieh Karimi, Andy T. Marshall, Rumi Nakamura, Haoming Liang, Vadim M. Uritsky, Arya Afshari, Dominic S. Payne   +27 more
doaj   +1 more source

IHI SPACE Activities

, 1996
In: SPACE for a new cooperation between Italy and Japan. p.114-127Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome / CNR - Consiglio Nazionale delle ...
Kitamura, Y., Consiglio Nazionale delle Ricerche, Milan (Italy). Istituto per Ricercahe sulla Propulsione e l'Energetica - CNPM -   +1 more
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source