Results 181 to 190 of about 23,552,421 (303)

A new era for supernova science with the James Webb Space Telescope [PDF]

Justin D. R. Pierel, David Coulter, Christa DeCoursey, James M. DerKacy, Ori Dosovitz Fox, Melissa Shahbandeh, Matthew R. Siebert, Michael Engesser, Conor Larison, Thomas Moore, A. Rest, Rodrigo Angulo, M. Dulude, Eiichi Egami, M. Griggio, Mitchell Karmen, Xiaolong Li, Estefania Padilla Gonzalez, Koji Shukawa, Louis-Gregory Strolger   +19 more
openalex   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Structural compression and entorhinal vulnerability: Linking tentorial adjacency to tau burden and dementia progression. [PDF]

Alzheimers Dement
Zhang L, Franceschi AM, Crary JF, Provenzano FA, Alzheimer's Disease Neuroimaging Initiative.   +4 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Evaluating Time-Space Methodologies to Detect Clusters of HIV Transmission: A Comparison of Advanced Methods in Washington State, 2010-2022. [PDF]

J Acquir Immune Defic Syndr
Erly S, Yan H, Holte S, Mei Y, Kerani RP.   +4 more
europepmc   +1 more source

A Sign in Space part 2, a new simulated First Contact scenario engaging the global scientific SETI network, and integrating deep space technologies into SETI search [PDF]

Daniela de Paulis, Andrea Melis, Daniel Estévez   +2 more
openalex   +1 more source