Results 151 to 160 of about 2,298,846 (310)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Neuropsychiatric Tolerability of Long-Acting Cabotegravir and Rilpivirine in People With HIV With Prior INSTI-Related CNS Toxicity: A Real-World Cohort Study. [PDF]

Open Forum Infect Dis
Rosas Cancio-Suárez M, Moreno A, Terrón SDC, Vivancos MJ, Vélez Díaz-Pallarés M, Casado JL, Cano C, Navarro-Soler R, Moreno S, Pérez-Elías MJ.   +9 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Fingerprints Encode Risk for Bipolarity. [PDF]

Bipolar Disord
Salvador R, García-León MÁ, Rodriguez-Jimenez R, Del Olmo-Encabo P, Barbosa L, Aquino-Servín A, Sotero-Moreno A, Fatjó-Vilas M, Jaurrieta-Guarner N, Sánchez M, Corte-Souto C, Rojo A, Rebolleda-Gil C, Correa-Ghisays P, Balanzá-Martínez V, Caride-Padilla C, Sarró S, Feria-Raposo I, Sánchez-Cabezudo Á, Jiménez-Rodríguez O, Torres ML, Moreno-Comellas R, Navarro B, Del Olmo-Romero F, Larraz-Romeo JA, Pomarol-Clotet E.   +25 more
europepmc   +1 more source

The Effect of the 2004 and 2007 EU Enlargement on the Spanish Labour Market [PDF]

The 2004 and 2007 EU enlargement has led to a significant increase in the immigration flow to Spain. Individuals from the new-EU-12 countries accounted for no more than 10% of the whole Spanish immigrant population in 2004, but by 2008 they accounted for
de la Rica, Sara
core  

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Long-term refined genomic analysis of tuberculosis clusters to distinguish between ongoing transmission, reactivations or diagnostic delays, Almería, Spain, 2003 to 2024. [PDF]

Euro Surveill
Rodríguez-Grande C, Vallejo-Godoy S, Martínez-Lirola M, Saleeb SM, Herranz M, Buenestado-Serrano S, Marcos-Abellán A, Barroso-García P, Rueda Nieto S, Escabias-Machuca F, Esteban-García AB, Cabezas Fernández MT, Garrido-Cárdenas JA, Muñoz P, Pérez-Lago L, García de Viedma D.   +15 more
europepmc   +1 more source

Residential electricity demand for Spain: new empirical evidence using aggregated data [PDF]

This paper presents an empirical analysis on the residential demand for electricity. This analysis has been performed using aggregate panel data at the province level for 47 Spanish provinces for the period from 2000 to 2008.
Blazquez Leticia, Massimo Filippini, Nina Boogen   +2 more
core  

Integrated Visible Light and Oxidant Protection Through Multifunctional Sunscreens

Advanced Healthcare Materials, EarlyView.
High‐energy visible radiation (HEVR), although less energetic than UV light, penetrates deeper into the skin and contributes to photoaging, pigmentation disorders, and oxidative stress. The development of new HEVR‐targeted filters, therefore, represents not only a scientific challenge but also a pressing public health and cosmetic industry need.
Beatriz Peñín, Raúl Losantos, Ignacio Funes‐Ardoiz, Diego Sampedro   +3 more
wiley   +1 more source

Do conditional marketing authorisations actually accelerate patient access? Time-to-access of conditional vs. standard marketing authorisations in Italy, Spain, and Germany. [PDF]

J Pharm Policy Pract
Ardito V, Falk L, Gasol Boncompte M, Pontes C, Robinson J, Schreyögg J, Ciani O.   +6 more
europepmc   +1 more source