Results 111 to 120 of about 2,565,182 (287)
[p.4] Values at stake from the new water culture = Valors en joc des de la nova cultura de l'aigua[p.10] The role of schools in the future of water = El paper de l'àmbit escolar.
Arrojo Agudo, Pedro +11 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Monstrous Figurines, of BMAC, and the Dragon Myth: From a Meteoritic Headband to Rig Veda Mythology
Oxus “Scarface”, a small statuette from the Bactria–Margiana Archaeological Complex culture (Middle Bronze Age of Central Asia) preserved at the Metropolitan Museum (New York), wears a meteoritic iron headband like a comparable specimen preserved in Le ...
Albert Jambon
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Compared with traditional mariculture methods such as pond culture and common cage culture, the water quality and environment quality of far-reaching sea cage culture area are better, and the plankton density is higher, which can achieve the environment ...
Huangming WU +3 more
doaj
Aquaculture Asia, Vol. 8, No. 1, pp.1-58, January-March 2003 [PDF]
*Table of Contents* Sustainable Aquaculture Fertilization, soil and water quality management in small-scale ponds part II:Soil and water quality management S.
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Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Preliminary studies on bamboo floating cage and net enclosure culture in Kainji Lake basin [PDF]
The main objective of this paper is to introduce bamboo floating cage and net enclosure fish culture technology aimed at producing fish from almost all available inland bodies of water in Nigeria.
Otubusin, S.
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Strategies to harmonize urbanization and flood risk management in deltas [PDF]
In many countries, important economic centres and major cities are located in a flood-prone area at the confluence of a large river and the sea. The expansion of these cities increases the risk of major flood disasters, a risk that is further increased ...
Camiel Van Drimmelen +2 more
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