Results 111 to 120 of about 2,565,182 (287)

Water [PDF]

open access: yes, 2008
[p.4] Values at stake from the new water culture = Valors en joc des de la nova cultura de l'aigua[p.10] The role of schools in the future of water = El paper de l'àmbit escolar.
Arrojo Agudo, Pedro   +11 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Monstrous Figurines, of BMAC, and the Dragon Myth: From a Meteoritic Headband to Rig Veda Mythology

open access: yesHeritage
Oxus “Scarface”, a small statuette from the Bactria–Margiana Archaeological Complex culture (Middle Bronze Age of Central Asia) preserved at the Metropolitan Museum (New York), wears a meteoritic iron headband like a comparable specimen preserved in Le ...
Albert Jambon
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Present Situation and Development Countermeasures of Far-reaching Marine Aquaculture in Fujian Province

open access: yesHaiyang Kaifa yu guanli, 2023
Compared with traditional mariculture methods such as pond culture and common cage culture, the water quality and environment quality of far-reaching sea cage culture area are better, and the plankton density is higher, which can achieve the environment ...
Huangming WU   +3 more
doaj  

Aquaculture Asia, Vol. 8, No. 1, pp.1-58, January-March 2003 [PDF]

open access: yes, 2003
*Table of Contents* Sustainable Aquaculture Fertilization, soil and water quality management in small-scale ponds part II:Soil and water quality management S.

core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Preliminary studies on bamboo floating cage and net enclosure culture in Kainji Lake basin [PDF]

open access: yes, 1985
The main objective of this paper is to introduce bamboo floating cage and net enclosure fish culture technology aimed at producing fish from almost all available inland bodies of water in Nigeria.
Otubusin, S.
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Strategies to harmonize urbanization and flood risk management in deltas [PDF]

open access: yes
In many countries, important economic centres and major cities are located in a flood-prone area at the confluence of a large river and the sea. The expansion of these cities increases the risk of major flood disasters, a risk that is further increased ...
Camiel Van Drimmelen   +2 more
core  

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