Results 131 to 140 of about 2,565,182 (287)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Development of freshwater prawn (Macrobrachium rosenbergii) seed production and culture technology in the Mekong Delta Region of Vietnam: A review of the JIRCAS Project at Cantho University. [PDF]
, 2004 The Mekong Delta of Vietnam is a region rich in aquatic resources having high potential for aquaculture development. Inland aquaculture in the Mekong Delta has greatly increased since the last decade.
Hai, Tran Ngoc +5 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
VEIL Ballarat centre structural plan [PDF]
This report looks at the future devlopment in Ballerat, Victoria. New forms of urban planning, housing and also transport and use of natural resouces are some of the major topics covered. (1) BALLARAT - THE LOCALLY PRODUCTIVE CITY Goal: ...
Dianne Moy
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On-farm trials with rice fish cultivation in the west Kano rice irrigation scheme, Kenya [PDF]
, 2006 The viability of integrating rice farming with fish culture was studied in ten (10) rice plots. The on-farm research was done during one rice-growing season starting May 2003.
Auma, E.O., Rasowo, J.
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RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Spotlight on Technology: Development of an Autonomous Aquarium System for Maintaining Deep Corals [PDF]
Oceanography, 2009 Keeping deep corals alive under optimum water temperature and quality conditions is not an easy task. It is important to achieve a balance among a high-water renewal rate, constant water temperature, flow speed, and nutrient concentrations (especially ...
Alejandro Olariaga +3 more
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Commercial mariculture of Oreochromis niloticus using net cages [PDF]
, 1987 The culture of tilapia has a long history in Africa. Fossil remains of members of the genus have been found which are about 18 million years old (Fryer and Iles, 1972).
Fineman-Kalio, A.S.
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