Results 21 to 30 of about 837,324 (218)

Chemical Investigations of a Deep Water Marine-Derived Fungus: Simple Amino Acid Derivatives from an sp

open access: yesNatural Product Communications, 2007
The saltwater culture of an Arthrinium sp. derived from a marine sediment collected at −550 meters was a source of tyrosol ( 1 ) and a new compound, tyrosol carbamate ( 2 ). This is only the third report of novel secondary metabolites discovered from the
Jeffrey T. Gautschi   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Water Sustainability among Secondary Education Teachers: Perspectives from Two Hispanic Cities

open access: yesAustralian Journal of Environmental Education
This article explores how water conditions in geographical contexts could influence the construction of teachers’ professional identities and, consequently, their knowledge and beliefs about water sustainability.
Alejandra Ramírez-Segado   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Microbial colonization and community stability in a marine post-smolt RAS inoculated with a commercial starter culture

open access: yesAquaculture Reports, 2021
The performance of a commercial starter culture was investigated in a new marine post-smolt RAS, analyzing the microbial communities of 100 samples collected monthly over a year from biofilter biofilm carriers, tank wall biofilm, production water and ...
K. Drønen   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The protection of water in Morocco: Vector of Sustainable development [PDF]

open access: yesمجلة الاجتهاد للدراسات القانونية والاقتصادية, 2020
Water represents an unavoidable resource, a global challenge and a risky situation for the majority of countries. The socio-economic activities depend on it when it is controlled, it could be synonymous with sustainability and progress.
Aicha Ajrar
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Viewpoint – The Next Nexus? Environmental Ethics, Water Policies, and Climate Change

open access: yesWater Alternatives, 2010
Water policies are based on ethical assumptions, and efforts to promote more sustainable policies need to address those underlying values. The history of water policies from 'command-and-control' to more ecological approaches reveals an ethical evolution,
David Groenfeldt
doaj  

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