Results 61 to 70 of about 2,549,913 (287)
Embracing Complexity: Creating Cultural Change Through Education for Sustainability [PDF]
, 2006 Campus Kindergarten in Brisbane, Australia, is a community-based organisation for children and families that has embraced change through the evolution of its internationally acclaimed ‘Sustainable Planet Project’. The centre initiated the project in 1997,
Davis, Julie, Gibson, Megan
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
BMGN: Low Countries Historical Review, 2009 Water and Dry Land Water management has always been a major concern. Dutch pragmatism certainly has roots in water management, but it is also rooted in the culture of meetings of the Dutch cities and in the attitude of the peasant who produced for the ...
P.J.E.M. van Dam
doaj +1 more source
Aquaculture Asia, Vol.13, No.3, pp.1-60, July-September 2008 [PDF]
, 2008 Comments on possible improvements to carp culture in Andhra Pradesh. Aquaculture and environmental issues in the region of Nai Lagoon, Ninh Hai district,Ninh Thuan province, Viet Nam. Climate change impacts on fi sheries and aquaculture.
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Social movements in sustainability transitions : identity, social learning & power in the Spanish & Turkish water domains / [PDF]
, 2010 Descripció del recurs: el 02 de novembre de 2010Dominant economic growth and nation-state building practices are often based on detaching individuals from other individuals and communities from their natural environment in which their livelihoods used to
Ilhan, Akgün +1 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
New Microbes and New Infections, 2020 Microbiology has been largely developed thanks to the discovery and optimization of culture media. The first liquid artificial culture medium was created by Louis Pasteur in 1860.
M. Bonnet +3 more
doaj +1 more source
Small fish, big money: conflicts evolving around new fishing techniques and old fishing rights at the shores of Lake Chad, Nigeria [PDF]
, 2006 Dumba-fishing was invented at Lake Chad about 10 years ago by immigrant fishermen from Mali and Nigerian Hausaland. The new technique brought about a new era of Lake Chad fishery, characterised by social and institutional changes.
Krings, Matthias
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source