Results 61 to 70 of about 2,565,182 (287)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Water en Land

open access: yesBMGN: Low Countries Historical Review, 2009
Water and Dry Land Water management has always been a major concern. Dutch pragmatism certainly has roots in water management, but it is also rooted in the culture of meetings of the Dutch cities and in the attitude of the peasant who produced for the ...
P.J.E.M. van Dam
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

A field report on Water and Irrigation Engineering touât And Gourera region (Algeria) [PDF]

open access: yesJournal of General Union of Arab Archaeologists, 2019
A though water is certainly scarce on the surface of the desert it can be found at the subterranean level. Humans, thousands of years ago, came up with an ingenious system that ensured water for their settlements and for irrigation of their vegetated ...
D.Djamel Annak
doaj   +1 more source

Social movements in sustainability transitions : identity, social learning & power in the Spanish & Turkish water domains / [PDF]

open access: yes, 2010
Descripció del recurs: el 02 de novembre de 2010Dominant economic growth and nation-state building practices are often based on detaching individuals from other individuals and communities from their natural environment in which their livelihoods used to
Ilhan, Akgün   +1 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Bacterial culture through selective and non-selective conditions: the evolution of culture media in clinical microbiology

open access: yesNew Microbes and New Infections, 2020
Microbiology has been largely developed thanks to the discovery and optimization of culture media. The first liquid artificial culture medium was created by Louis Pasteur in 1860.
M. Bonnet   +3 more
doaj   +1 more source

Reflection 8 [PDF]

open access: yes, 2010
The Third International Forum for Next Generation、The Establishment of a New Department for Research on East Asian Culture : As a New Research Base for the Study on Cultural Interaction Studies、Report on the Field Work in Amakusa、International Symposium ...
Institute For Cultural Interaction Studies Kansai University
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Improved detection of Rhodococcus coprophilus with a new quantitative PCR assay [PDF]

open access: yes, 2018
Agricultural practices, such as spreading liquid manure or the utilisation of land as animal pastures, can result in faecal contamination of water resources.
Auckenthaler, Adrian   +7 more
core  

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