Results 71 to 80 of about 2,565,182 (287)

Colonizing the Thames [PDF]

, 2011
A case in which colonial engineers and administrators, working in concert with engineers and officials based in Britain, sought to employ the "tools of empire" on the ...
John Broich
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Understanding the drying mechanism of straw substrate culture block: Physicochemical properties, pore structure, and drying optimization

Heliyon
As a new type of agricultural waste block substrate utilization, the initial wet base state of the substrate culture block needs to be dried. Therefore, studying the drying mechanism of substrate culture block is critical.
Qian Cheng, Zihui Liu, Jiayi Sun, Shuo Li, Chongxuan Zhao, Junfeng Su, Qingyu Liu, Mingjin Xin, Dejun Liu   +8 more
doaj   +1 more source

Aquaculture and marketing of the Florida Bay Scallop in Crystal River, Florida [PDF]

, 2000
The overall goal of this study was to develop a new fishery resource product through open-water aquaculture for the west coast of Florida that would compete as a non-traditional product through market development.
Adams, Charles, Blake, Norman J., Degner, Robert, Moss, Susan D., Sturmer, Leslie, Sweat, Don   +5 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Transforming cities into sustainable and healthy territories starts with the “Culture of water”: learning from traditional peoples and communities of the Carapitanga river basin

Frontiers in Environmental Science
IntroductionIn a world where one in four individuals lacks assured access to water, this article investigates how the experiences of Traditional Peoples and Communities (TPCs) can serve as a guiding light in the search for solutions to water disparities,
Júlia Borges, Júlia Borges, Edmundo Gallo, Edmundo Gallo, Simonne Teixeira   +4 more
doaj   +1 more source

Cultural Factors as Co-Determinants of Participation in River Basin Management

Ecology and Society, 2007
Finding a place for public participation in the policies and practices of European river basin management planning is a challenge for the authorities in the participating countries and territories. Understanding the relation between national culture, the
Bert Enserink, Mita Patel, Nicole Kranz, Josefina Maestu   +3 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Water Saving in Rice-Wheat Systems

Plant Production Science, 2005
Water shortage is a major constraint to sustaining and increasing the productivity of rice-wheat systems. Saving water can be elusive in that reducing seepage, percolation and runoff losses from fields does not necessarily save water if it can be ...
E. Humphreys, C. Meisner, R. Gupta, J. Timsina, H.G. Beecher, Tang Yong Lu, Y.-S. Yadvinder-Singh, M.A. Gill, I. Masih, Zheng Jia Guo, J.A. Thompson   +10 more
doaj   +1 more source

Effects of organochlorine pesticides (OCPs) on survival and edibility of loaches in the World Heritage Honghe Hani Rice Terraces, China

Aquaculture Environment Interactions, 2019
A new rice-loach co-culture system was introduced into the Honghe Hani Rice Terraces (HHRT), China, to promote sustainable development of this World Heritage region. However, little is known about the survival of loaches in this area and whether they are
Song, C, Zhang, J, Hu, G, Yin, Y, Qiu, L, Fan, L, Zheng, Y, Meng, S, Zhang, C, Chen, J   +9 more
doaj   +1 more source