Results 31 to 40 of about 90,270 (301)

Preparing New World Monkeys for Laboratory Research [PDF]

ILAR Journal, 2006
New World monkeys represent an important but often poorly understood research resource. The relatively small size and low zoonotic risk of these animals make them appealing as research subjects in a number of areas. However, historic portrayal of many of these species as difficult to manage and handle is one of the factors that has limited their use ...
Tardif, Suzette, Bales, Karen, Williams, Lawrence, Moeller, Elisabeth Ludlage, Abbott, David, Schultz-Darken, Nancy, Mendoza, Sally, Mason, William, Bourgeois, Sabrina, Ruiz, Julio   +9 more
openaire   +4 more sources

Computational modeling of oxytocin-receptors interactions with the common marmoset Callithrix jacchus Pro8OT variant [PDF]

Genetics and Molecular Biology
The oxytocinergic system plays a crucial role in regulating physiological and behavioral processes, making it a key component of neurobiology in both humans and animals.
Bruno Veber, Rodrigo dos Santos Fuscaldo, Pedro Vargas-Pinilla, Bruna Oliveira Missaggia, Maria Cátira Bortolini, Paulo Augusto Netz   +5 more
doaj   +1 more source

Intestinal capillariasis in New World monkeys

Journal of Medical Primatology, 1994
Two cases of intestinal capillariasis have been identified at necropsy in a squirrel monkey and a capuchin monkey born and raised in captivity. The parasites are described as far as possible from the histopathological slides or intestinal contents, and their relationship to other intestinal capillarids, especially those of primates, is discussed.
Brack, M., Gass, H., Stirnberg, E.
openaire   +3 more sources

Timing the Origin of New World Monkeys [PDF]

Molecular Biology and Evolution, 2003
The origin of New World monkeys (Infraorder Platyrrhini) has been an extensively debated issue. In this study, we analyzed mitochondrial genomes from Cebus (Platyrrhini), Homo, Hylobates, Pan, Pongo (Hominoids), Macaca, Papio (Cercopithecoids), and Tarsius (outgroup) to investigate this matter.
Carlos G, Schrago, Claudia A M, Russo
openaire   +2 more sources

Not knowing what one knows: A Meaningful failure of metacognition in capuchin monkeys [PDF]

Animal Behavior and Cognition, 2018
Metacognition encompasses the processes of monitoring representational and perceptual states and controlling information-gathering behaviors. Metacognition is considered one of humans’ most sophisticated abilities, and it has been a growing area of focus
Travis R. Smith , J. David Smith , Michael J. Beran   +2 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Characterisation of the hepatitis B virus cross-species transmission pattern via Na+/taurocholate co-transporting polypeptides from 11 New World and Old World primate species. [PDF]

PLoS ONE, 2018
The hepatic Na+/taurocholate co-transporting polypeptide (NTCP in man, Ntcp in animals) is the high-affinity receptor for the hepatitis B (HBV) and hepatitis D (HDV) viruses.
Simon F Müller, Alexander König, Barbara Döring, Dieter Glebe, Joachim Geyer   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Evolution of the hepcidin gene in primates

BMC Genomics, 2008
Background Hepcidin/LEAP-1 is an iron regulatory hormone originally identified as an antimicrobial peptide. As part of a systematic analysis of the evolution of host defense peptides in primates, we have sequenced the orthologous gene from 14 species of ...
Tossi Alessandro, Milanese Michele, Pontillo Alessandra, Segat Ludovica, Crovella Sergio   +4 more
doaj   +1 more source

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

Advanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin, Wenbing Jiang, Kai Xin Thong, Zeynep Ulker, Brihitejas Patel, Cynthia Yu‐Wai‐Man   +5 more
wiley   +1 more source