Results 91 to 100 of about 10,800,885 (305)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Обрядові традиції різдвяно-новорічного циклу: локальні комплекси та їхні ареали на Середньому Поліссі України (за матеріалами картографування)

open access: yesПростір в історичних дослідженнях
У статті розглянуто сільське кладовище як сакральне місце у віруваннях українців Полісся. Звернуто увагу на причини посухи, зокрема, при похованні на кладовищі самогубців (вішальників, потопельників).
Надія Ковальчук
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Alumni of the First Ten Years of Nippon Foundation/GEBCO Postgraduate Certificate in Ocean Bathymetry Training Program [PDF]

open access: yes, 2014
The Nippon Foundation/GEBCO Training Programme is a twelve-month course leading to a Postgraduate Certificate in Ocean Bathymetry (PCOB). It is held at the University of New Hampshire, USA and is helping to develop a new generation of seafloor mappers ...
Wigley, Rochelle A.
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Diversity-Related, Student-Led National Medical Organizations: Leadership Opportunities for Learners

open access: yesMedEdPORTAL
Introduction In light of the lack of diversity in academic medicine leadership, diversity-related, student-led national medical organizations (NMOs) provide a space for solace and reprieve among common peers while providing an opportunity to develop ...
Nicholas N. Brutus   +7 more
doaj   +1 more source

The University of Pittsburgh: a three and three-quarter-year experience with cadaveric renal transplantation under the point system. [PDF]

open access: yes, 1989
Eight hundred and sixty kidney transplants were performed at the University of Pittsburgh over a 3.75-year period between January 1, 1986 and October 19, 1989.
Fung, JJ   +7 more
core  

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