Results 101 to 110 of about 10,800,210 (238)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Diversity-Related, Student-Led National Medical Organizations: Leadership Opportunities for Learners

MedEdPORTAL
Introduction In light of the lack of diversity in academic medicine leadership, diversity-related, student-led national medical organizations (NMOs) provide a space for solace and reprieve among common peers while providing an opportunity to develop ...
Nicholas N. Brutus, Dennis J. Spencer, Derek Huell, Yaritzy M. Astudillo, Austen Ott, Joyce H. Lee, Alec J. Calac, John P. Sánchez   +7 more
doaj   +1 more source

Pay as you save (PAYS) [PDF]

, 2008
Policy Leadership Initiative Year III Addressing Energy Challenges for Low-income Families in Northern New ...
Cillo, Paul A.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Ringing in the new year with an investment bust? [PDF]

Investments
Kevin L. Kliesen
core  

RWU Gabelli School of Business Introduces Accelerated Master of Business Administration Program [PDF]

, 2017
The new program enables students to earn their master’s degree just one year after completing their bachelor ...
Siliezar, Juan
core   +1 more source

New insights into foreground analysis of the WMAP five-year data using FASTICA

, 2009
In this paper, we present a foreground analysis of the WMAP 5-year data using the FASTICA algorithm, improving on the treatment of the WMAP 3-year data in Bottino et al 2008. We revisit the nature of the free-free spectrum with the emphasis on attempting
A. J. Banday, Baccigalupi, Banday, Bennett, Bonaldi, Bottino, Chiang, D. Maino, Davies, Delabrouille, Delabrouille, Dickinson, Dobler, Dobler, Dobler, Draine, Eriksen, Finkbeiner, Finkbeiner, Finkbeiner, Gold, Górski, Hansen, Haslam, Hinshaw, Hinshaw, Hyvärinen, Hyvärinen, Kim, M. Bottino, Maino, Maino, Park, Patanchon, Tegmark, Wright   +35 more
core   +1 more source

Plasma cell-free DNA testing in diagnosing Listeria rhombencephalitis in a CSF PCR-negative patient: a case report

BMJ Neurology Open
Background The aetiologic identification of central nervous infections, including Listeria, remains challenging as most pathogens are not identified in meningoencephalitis cases despite advances in molecular diagnostics. Plasma next-generation sequencing
Melissa Gitman, Tam Tran, Cameron Yi, Gabriela Keeton, Allison Navis   +4 more
doaj   +1 more source

New England Genetics Collaborative Results of the Stakeholder Survey for Project Year Four [PDF]

, 2012
Stakeholder feedback offers a range of critical and helpful insights into the potential next steps for the collaborative as it carriers on activities for Project Year Five and plans for a new grant application.
Antal, Peter
core   +1 more source

New year, new approaches [PDF]

Journal of Public Health, 2013
Selena F, Gray, Gabriel M, Leung
openaire   +2 more sources