Results 81 to 90 of about 10,800,885 (305)
British Journal of General Practice, 2014 In a few months’ time the UK will have a new government. That much is certain, but the political, economic, and medical landscape beyond May 2015 is anything but. In the meantime the health service has become a political football as never before. Bidding wars rage over the number of new GPs that the parties will produce; by magic, of course, for where ...
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
New year, new advice, new news
Revista Brasileira de Ortopedia (English Edition), 2010 We start another year with this issue of the RBO, which now contains a greater number of studies. This was decided by the Editorial Board and the new directorate of the SBOT, in view of the ever greater number of studies sent for publication: instead of more issues, a journal with a greater number of studies.
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PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
BMJ, 2004 New Year's Day is nothing but an arbitrary day that, for instance, was celebrated by the Babylonians at the new moon after the spring equinox (and next year, the 1 Nisanu 2631 will be on what we call 9 April 2005 (www.cf-software.com/other.html)). On 1 January no check, no pause, no planetary escapement in the celestial clockwork will take place as our
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
New England Genetics Collaborative Results of the Stakeholder Survey for Project Year Four [PDF]
, 2012 Stakeholder feedback offers a range of critical and helpful insights into the potential next steps for the collaborative as it carriers on activities for Project Year Five and plans for a new grant application.
Antal, Peter
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Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
International Journal of Medical StudentsBackground: The treatment of urinary tract infections (UTIs) has contributed to the rise of antibiotic resistance. Antibiotic appropriateness in the outpatient setting is lower than expected.
Kira A. LeBron +4 more
doaj +1 more source