Results 51 to 60 of about 1,644,009 (334)

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Early‐phase amyloid PET reproduces metabolic signatures of cognitive decline in Parkinson's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Recent work suggests that amyloid beta (Aβ) positron emission tomography (PET) tracer uptake shortly after injection (“early phase”) reflects brain metabolism and perfusion.
William W. T. Aye, Megan R. Stark, Kyla‐Louise Horne, Leslie Livingston, Sophie Grenfell, Daniel J. Myall, Toni L. Pitcher, Mustafa M. Almuqbel, Ross J. Keenan, Wassilios G. Meissner, John C. Dalrymple‐Alford, Tim J. Anderson, Campbell Le Heron, Tracy R. Melzer   +13 more
doaj   +1 more source

Protocol for the INFORM ASTHMA Trial: budesonide–formoterol reliever in adults with asthma on maintenance inhaled corticosteroid

ERJ Open Research
Background International asthma guidelines recommend inhaled corticosteroid (ICS)/formoterol in preference to short-acting β2-agonist (SABA) reliever-based regimens as reliever therapy in adults and adolescents of all asthma severities.
Jonathan Noble, Orlagh Bean, Pepa Bruce, Melissa Black, Ross Sayers, Ryan Cullen, Bianca Black, Mark Holliday, Louis Kirton, Blake Perry, Allie Eathorne, Ian Pavord, Mark Weatherall, Richard Beasley   +13 more
doaj   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Further validation of the New Zealand test of adult reading (NZART) as a measure of premorbid IQ in a New Zealand sample [PDF]

, 2013
Premorbid IQ estimates are used to determine decline in cognitive functioning following trauma or illness. This study aimed to: 1) further validate the New Zealand Adult Reading Test (NZART) in a New Zealand population and compare its performance to the ...
Barker-Collo, Suzanne, Lichtwark, Irene Tatjana, Starkey, Nicola J.   +2 more
core   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Patterns of asthma medication use and hospital discharges in New Zealand

Journal of Allergy and Clinical Immunology: Global
Background: In New Zealand a progressive increase in budesonide/formoterol dispensing, accompanied by a reduction in dispensing of short-acting β2-agonists (SABAs), inhaled corticosteroids (ICSs), and other ICS/long-acting β2-agonists (ICSs/LABAs ...
Jonathan Noble, MBBS, Lee Hatter, MBBS, Allie Eathorne, BSc, Thomas Hills, DPhil, Orlagh Bean, MBBS, Pepa Bruce, MBBS, Mark Weatherall, FRACP, Richard Beasley, DSc   +7 more
doaj   +1 more source

Tolerability of Nasal Delivery of Humidified and Warmed Air at Different Temperatures: A Randomised Double-Blind Pilot Study

Pulmonary Medicine, 2016
Objectives. Delivery of warmed, humidified air via nasal high flow therapy could potentially reduce replication of temperature-sensitive viruses in the upper respiratory tract.
Susan Bibby, Sumeet Reddy, Terrianne Cripps, Steve McKinstry, Mark Weatherall, Richard Beasley, Janine Pilcher   +6 more
doaj   +1 more source

Marker Selection in Multivariate Genomic Prediction Improves Accuracy of Low Heritability Traits

Frontiers in Genetics, 2020
Multivariate analysis using mixed models allows for the exploration of genetic correlations between traits. Additionally, the transition to a genomic based approach is simplified by substituting classic pedigrees with a marker-based relationship matrix ...
Jaroslav Klápště, Heidi S. Dungey, Emily J. Telfer, Mari Suontama, Mari Suontama, Natalie J. Graham, Yongjun Li, Yongjun Li, Russell McKinley   +8 more
doaj   +1 more source