Results 121 to 130 of about 404,820 (269)

Stillbirth and newborn data quality and use and related input and process factors: findings of the IMPULSE study in Uganda. [PDF]

J Glob Health
Wasswa R, Cora LG, Kananura RM, Lochoro P, Mugahi R, Ogwal J, Ebong C, Abathun F, Fisshea D, Minja J, Ayele M, Mouhamadou O, Mariani I, Tognon F, Lawn JE, Putoto G, Shamba D, Waiswa P, Lazzerini M.   +18 more
europepmc   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source

P560: Implementing homocysteine into first-tier mass spectrometry tests in newborn screening for detection of homocystinurias in New York State

Genetics in Medicine Open
Jing Xiao, C. Austin Pickens, Konstantinos Petritis, Matthew Wojcik, Carlos Saavedra-Matiz, Joseph Orsini, Michele Caggana   +6 more
doaj   +1 more source

Maternal and Newborn Group B <i>Streptococcus</i> Serology in the United States and South Africa. [PDF]

Open Forum Infect Dis
Pahud BA, Madhi SA, Klein NP, Cai B, Scully IL, Gaylord M, Feng Y, Jiang HQ, Swanson KA, Anderson AS, Gurtman A, Munjal I.   +11 more
europepmc   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Acceptance of the respiratory syncytial virus infant monoclonal antibody nirsevimab among post-partum women in Italy. [PDF]

Hum Vaccin Immunother
Angelillo S, Miraglia Del Giudice G, Della Polla G, Angelillo IF, Collaborative Working Group.   +4 more
europepmc   +1 more source

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

Advanced Science, EarlyView.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar, Carlos Gomez, Giancarlo Asencio, Suresh Pallikkuth, Ashutosh Agarwal   +4 more
wiley   +1 more source

Exploration of factors affecting parent-infant closeness and separation in hospitals in Nepal - a qualitative study. [PDF]

BMC Pregnancy Childbirth
Brunell O, Bergström A, Gurung R, Eriksson L.   +3 more
europepmc   +1 more source

Mapping Steroidogenic Perturbations Under Endocrine Disruptor Mixtures Across Demographic Subgroups: Structural and Metabolomic Insights

Advanced Science, EarlyView.
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen, Lei Huang, Yingtong Jiang, Guohong Zhao, Mengyuan Zhu, Xiulian Lu, Lang Lang, Akinpelumi Oluwatobiloba Esther, Longhao Fan, Yuqi Jiang, Chang Sun, Xiaoling Zhang, Kun Zhou, Xiaoming Ji, Minjian Chen   +14 more
wiley   +1 more source

Association between PFAS and renal function indicators in cord blood of newborns: modifying effects of newborn sex and maternal factors. [PDF]

Ann Med
Yan W, Xu P, Xu Y, Yang W, Huang Q, Mzava SM, Bigambo FM, Wang D, Wang X.   +8 more
europepmc   +1 more source