Results 211 to 220 of about 1,348,248 (398)

Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss

Advanced Science, EarlyView.
 . ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao, Xiang Li, Yaqi Liao, Liman Liu, Xian Gao, Hailiang Lin, Wenli Ni, Huawei Li, Yan Chen, Wenyan Li   +9 more
wiley   +1 more source

Incidental Detection of Glutamate Formiminotransferase Deficiency Through Newborn Screening in a Clinically Asymptomatic Infant: Molecular Findings and Counseling Considerations. [PDF]

Cureus
Baheer Abdulwahhab S, Ben Omran M, A Aldirbashi OY.   +2 more
europepmc   +1 more source

Newborn screening for lysosomal storage disorders by tandem mass spectrometry in North East Italy

Journal of Inherited Metabolic Disease, 2018
Alberto B. Burlina, G. Polo, L. Salviati, G. Duro, C. Zizzo, A. Dardis, B. Bembi, C. Cazzorla, L. Rubert, R. Zordan, R. Desnick, Alessandro P. Burlina   +11 more
semanticscholar   +1 more source

Hierarchical Channeled Graphitized Nanoarchitecture as a Diagnostic Platform for Maternal Fever Warning

Advanced Science, EarlyView.
This study presents a hierarchically channeled graphitized nanoarchitecture (HPGC‐Z67) as a novel nano‐diagnostic platform. It enables sensitive and efficient N‐glycan extraction from plasma, significantly reducing processing time and cost. The platform identifies pivotal N‐glycans to accurately differentiate between infectious and non‐infectious ...
Yiwen Lin, Ning Li, Heyuhan Zhang, Xufang Hu, Zhiqiang Liu, Chunhui Deng   +5 more
wiley   +1 more source

P560: Implementing homocysteine into first-tier mass spectrometry tests in newborn screening for detection of homocystinurias in New York State

Genetics in Medicine Open
Jing Xiao, C. Austin Pickens, Konstantinos Petritis, Matthew Wojcik, Carlos Saavedra-Matiz, Joseph Orsini, Michele Caggana   +6 more
doaj   +1 more source

Commentary: Newborns in Fragile and Humanitarian Settings: A Multi-Agency Partnership Roadmap

Journal on Education in Emergencies, 2021
Saverio Bellizzi, Lori McDougall, Sheila Manji, Ornella Lincetto   +3 more
doaj   +1 more source

Levels of care for maternal and neonatal healthcare: a scoping review. [PDF]

J Glob Health
Mackin S, Day LT, Dekker C, Gouse I, Maina M, Aluvaala J, Moran A, Revisioning Emergency Obstetric and Newborn Care (EmONC) levels-of-care workstream.   +7 more
europepmc   +1 more source

Comparison of the effects of postnatal PACAP treatment, enriched environment and perinatal stresses on the neurobehavioral development of newborn rats

, 2010
Reglődi Dóra
openalex   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Adverse Newborn Outcomes by Insurance Status Among Patients with Severe Maternal Morbidity in Maryland: 2020-2023. [PDF]

Healthcare (Basel)
Manandhar P, Wolfson C, Sheffield J, Phillips M, Graham E, Atlas R, Chin P, Olaku J, Duafala R, Cline BL, Burd I, Fahey J, Jones-Beatty K, Mehlhaff KM, Jones MB, Buchanan K, Carey ME, Chiang J, Argani C, Kelly E, Krout K, Madan I, Downey C, Kasirsky J, Richter AM, Starr H, Wynn JL, Creanga AA, Aziz KB.   +28 more
europepmc   +1 more source