Results 261 to 270 of about 925,982 (358)

Disclosing to parents newborn carrier status identified by routine blood spot screening [PDF]

, 2004
Dezateux, Carol, Kavanagh, Josephine, Lempert, Tami, Oliver, Sandy, Stewart, Ruth   +4 more
core   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

COMPLICATIONS OF OBLITERATIVE VERSUS RECONSTRUCTIVE VAGINAL SURGERY FOR PELVIC ORGAN PROLAPSE IN OCTOGENARIANS

Continence, 2023
C Coleman, K Bonasia, D Pascali, A Clancy   +3 more
doaj  

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

The genetic secrets revealed from canine fetal fluids obtained in mid-pregnancy. [PDF]

Sci Rep
Tal S, Bar-Gal GK.
europepmc   +1 more source

Artificial Internalizing Receptors for Targeted Degradation of Extracellular Proteins

Advanced Science, EarlyView.
Small organic molecules that are anchored into the lipid bilayer of a mammalian cell and have an exofacial recognition ligand can act as artificial internalizing receptors. These receptors are an efficacious tool to selectively capture and internalize cognate antibodies from the extracellular environment in a protein‐specific manner.
Ane B. Søgaard, Rikke Fabech Hansson, Mikkel Høj Nielsen, Alexander N. Zelikin   +3 more
wiley   +1 more source

Born Too Soon: Progress, priorities and pivots for preterm birth. [PDF]

Reprod Health
Ghebreyesus TA, Kanem N, Russell C, Clark H.   +3 more
europepmc   +1 more source

New Project Will Improve Newborn Screening for Heart Disease Throughout New England [PDF]

, 2012
Gianino, Matt
core   +1 more source

Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

Advanced Science, EarlyView.
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley   +1 more source

Measuring respectful maternal and newborn care in Nepal: Comparing linked observation and interview data- prospective cohort study. [PDF]

PLOS Glob Public Health
Basnet O, Sacks E, Kinney MV, Kc A.
europepmc   +1 more source