Results 191 to 200 of about 212,548 (293)

Correction to: Newborn Screening Followed By Early Treatment is Essential to Improve Survival in SCID. [PDF]

J Clin Immunol
Goebel GA, Cunha LAO, Minafra FG, Pinto JA.   +3 more
europepmc   +1 more source

Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response

Advanced Science, EarlyView.
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li, Jiajun Tan, Chuqing Zhou, Siyi Zhou, Yuanli Ye, Xinzhu Li, Xinyu Shen, Tian Xie, Mengyue Wang, Jingwei Jiang, Yiping Zhao, Xiao Xiang, Yong Zhou, Jun Wu, Cheng‐Ming Chuong, Mingxing Lei   +15 more
wiley   +1 more source

The storage and use of newborn babies' blood spot cards: a pubic consultation [PDF]

, 2005
Dezateux, Carol, Hargreaves, Katrina, Oliver, Sandy, Stewart, Ruth   +3 more
core   +1 more source

Newborn Screening Program for Spinal Muscular Atrophy in the Campania Region (Italy): Current Limitations and Potential Perspectives. [PDF]

Int J Neonatal Screen
Ambrosio A, Fioretti T, D'Andrea B, Pezone L, Bitetti I, Di Domenico C, Vallone S, Maiolo V, Cioce A, Giustino M, Varone A, Esposito G.   +11 more
europepmc   +1 more source

FGF9–FGFR2 Signaling via Osteocytes‐Preosteoblasts Crosstalks to Mediate Mechanotransduction‐Driven Intramembranous Osteogenesis in the Underdeveloped Maxilla

Advanced Science, EarlyView.
This study identifies osteocyte‐derived FGF9 as a mechanosensitive factor that impairs osteogenesis in the underdeveloped maxilla by inducing FGFR2 nuclear translocation in preosteoblasts. Mechanical stimulation reduces FGF9 secretion, relieving its inhibitory effect. These findings reveal a novel osteocyte–preosteoblast FGF9–FGFR2 axis in craniofacial
Yiwen Zhou, Lili Chen, Miaomiao Han, Peixiang Zhu, Yanyi Wang, Xuanxuan Yu, Tingyu Reng, Huijuan Wang, Baochao Li, Caixia Zhang, Ziwei Huang, Shuang Lin, Guoyun Wang, Jie Ge, Baosheng Guo, Huang Li   +15 more
wiley   +1 more source

A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate

Advanced Science, EarlyView.
Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao, Hui Zhang, Yidong Liu, Xianzhi Xu, Wei Liu, Zhaoqi Kang, Rong Xu, Shuang Hou, Ping Han, Chuanjuan Lü, Cuiqing Ma, Ping Xu, Chao Gao   +12 more
wiley   +1 more source

Analysis of the Effect of Demographic Variables on Lysosomal Enzyme Activities in the Missouri Newborn Screening Program. [PDF]

Int J Neonatal Screen
Vermette L, Washburn J, Klug T.
europepmc   +1 more source

Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
The aberrant adenosine metabolism leads to chemoresistance and immunosuppressive microenvironment. A versatile albumin‐polyplexes conjugated nanoparticle B‐PDEA@CPA is prepare for the codelivery of gemcitabine and siCD39. The nanoparticle releases gemcitabine‐loaded albumin upon microenvironment to achieve promoted penetration and cellular uptake ...
Hongrui Fan, Hongyi Chen, Haolin Song, Chufeng Li, Yu Wang, Zhenhao Zhao, Qin Guo, Xuwen Li, Mingxuan Liu, Tao Sun, Chen Jiang   +10 more
wiley   +1 more source

Survey of information resources on newborn blood spot screening for parents and health professionals: a systematic review [PDF]

, 2005
Hargreaves, Katrina, Oliver, Sandy, Stewart, Ruth   +2 more
core   +1 more source

Evaluation of <i>GLA</i> variants detected in newborn screening for Fabry disease using biomarker analysis. [PDF]

Mol Genet Metab Rep
Sawada T, Kido J, Tsukimura T, Sugawara K, Shiga T, Saito S, Togawa T, Inoue T, Watanabe Y, Hamada J, Sakuraba H, Nakamura K.   +11 more
europepmc   +1 more source