Results 291 to 300 of about 1,922,511 (410)

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Beyond Targeted Newborn Screening: A Nontargeted Metabolomics Workflow to Investigate Birthweight-Metabolome Correlations. [PDF]

Anal Chem
Asef CK, Moore SG, Pickens CA, Saavedra-Matiz CA, Orsini JJ, Petritis K, Gaul DA, Fernández FM.   +7 more
europepmc   +1 more source

The implementation of newborn screening for spinal muscular atrophy: the Australian experience

Genetics in Medicine, 2019
D. Kariyawasam, J. S. Russell, V. Wiley, I. Alexander, M. Farrar   +4 more
semanticscholar   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

P560: Implementing homocysteine into first-tier mass spectrometry tests in newborn screening for detection of homocystinurias in New York State

Genetics in Medicine Open
Jing Xiao, C. Austin Pickens, Konstantinos Petritis, Matthew Wojcik, Carlos Saavedra-Matiz, Joseph Orsini, Michele Caggana   +6 more
doaj  

Cost analysis of newborn screening for spinal muscular atrophy using digital PCR vs. MLPA. [PDF]

Mol Genet Metab Rep
Shekhawat DS, Mittal A, Singh K.
europepmc   +1 more source

Artificial Internalizing Receptors for Targeted Degradation of Extracellular Proteins

Advanced Science, EarlyView.
Small organic molecules that are anchored into the lipid bilayer of a mammalian cell and have an exofacial recognition ligand can act as artificial internalizing receptors. These receptors are an efficacious tool to selectively capture and internalize cognate antibodies from the extracellular environment in a protein‐specific manner.
Ane B. Søgaard, Rikke Fabech Hansson, Mikkel Høj Nielsen, Alexander N. Zelikin   +3 more
wiley   +1 more source

Newborn Screening for Gaucher Disease: Parental Stress and Psychological Burden. [PDF]

Int J Neonatal Screen
Cazzorla C, Gragnaniello V, Gaiga G, Gueraldi D, Puma A, Loro C, Benetti G, Schiavo R, Porcù E, Burlina AP, Burlina AB.   +10 more
europepmc   +1 more source

Mass Newborn Screening in Singapore—Position and Projections

, 2003
Roy Joseph
openalex   +2 more sources

Are PM6:Y6 Bulk Heterojunction Photoactive Films Cytocompatible and Electrically Stable in Biological Environments?

Advanced Electronic Materials, EarlyView.
PM6:Y6 organic photovoltaic films are systematically studied to understand their potential for use in bioelectronics. The films exhibit excellent stability in simulated physiological environments, enabling consistent power delivery and demonstrating compatibility with rat neurons and the choriallantoic membrane of chicken embryos.
Mathias Polz, Konrad Binter, Kaila M. Yallum, Thomas Rath, Marta Nowakowska‐Desplantes, Christa Schimpel, Gerhard Sommer, Nassim Ghaffari‐Tabrizi‐Wizsy, Natalie Banerji, Gregor Trimmel, Theresa Rienmüller   +10 more
wiley   +1 more source