Results 121 to 130 of about 1,360,274 (268)

High‐throughput, high‐fidelity reconstruction of whole mouse‐heart cytoarchitecture at cellular scale

The Journal of Physiology, EarlyView.
Abstract figure legend Experimental workflow of the dual‐camera light‐sheet microscope (dual‐mesoSPIM) pipeline. Intact adult mouse hearts undergo CUBIC‐based delipidation and refractive‐index matching, rendering the whole organ optically transparent (left).
Francesco Giardini, Chiara Palandri, Sofia Botti, Camilla Olianti, Paolo Mele, Niccolò Ballerini, Roberto Piersanti, Mauro Giacca, Peter Kohl, Callum M. Zgierski‐Johnston, Elisabetta Cerbai, Francesco Regazzoni, Leonardo Sacconi   +12 more
wiley   +1 more source

Australian Public Perspectives on Genomic Newborn Screening: Risks, Benefits, and Preferences for Implementation

International Journal of Neonatal Screening
Recent dramatic reductions in the timeframe in which genomic sequencing can deliver results means its application in time-sensitive screening programs such as newborn screening (NBS) is becoming a reality.
Fiona Lynch, S. Best, C. Gaff, L. Downie, Alison D. Archibald, C. Gyngell, I. Goranitis, Riccarda Peters, Julian Savulescu, S. Lunke, Zornitza Stark, D. Vears   +11 more
semanticscholar   +1 more source

NMDA receptor subunit‐dependent analysis of radiprodil inhibition in neonatal male rat substantia nigra dopaminergic neurons

British Journal of Pharmacology, Volume 183, Issue 23, Page 6767-6786, December 2026.
Abstract Background and Purpose Radiprodil is a GluN2B subunit selective NMDA receptor negative allosteric modulator which is currently under clinical investigation as a possible anti‐epileptic drug for paediatric use. Our goal was to investigate the inhibition of dopaminergic neuron NMDA responses by radiprodil.
Bangyuan Liu, Alasdair J. Gibb
wiley   +1 more source

NewSTEPs: The Establishment of a National Newborn Screening Technical Assistance Resource Center

International Journal of Neonatal Screening, 2017
As newborn screening (NBS) programs in the US implement expanded screening panels, utilize emerging technologies and identify areas for improvement, the need to establish and maintain a community engagement based national technical assistance center ...
Jelili Ojodu, Sikha Singh, Yvonne Kellar-Guenther, Careema Yusuf, Elizabeth Jones, Thalia Wood, Mei Baker, Marci K. Sontag   +7 more
doaj   +1 more source

Newborn screening for SCID and severe T lymphocytopenia in Europe.

Journal of Allergy and Clinical Immunology
Initiation of newborn screening (NBS) programs in Europe dates back to the 1960s. One of the most recent expansions of NBS programs was the addition of severe combined immunodeficiency (SCID) based on detection of T-cell receptor excision circles (TRECs).
M. Blom, Maarja Soomann, P. Soler-Palacín, A. Šedivá, A. Stray-Pedersen, R. Zetterström, C. Speckmann, A. Gennery, M. van der Burg   +8 more
semanticscholar   +1 more source

Morphometric analysis of postnatal lung development in the gray short‐tailed opossum (Monodelphis domestica): An ultrastructural study

The Anatomical Record, Volume 309, Issue 11, Page 3397-3415, November 2026.
Abstract An ultrastructural morphometric analysis of the postnatal development of the lung in the gray short‐tailed opossum (Monodelphis domestica) has been conducted to evaluate the morphofunctional status of this poorly developed marsupial lung immediately following parturition.
Kirsten Ferner
wiley   +1 more source

It Takes All of Us: How the Cystic Fibrosis Foundation Is Supporting States in Advancing Cystic Fibrosis Newborn Screening

International Journal of Neonatal Screening
The publication of Cystic Fibrosis Newborn Screening: A Systematic Review-Driven Consensus Guideline from the United States Cystic Fibrosis Foundation (CFF) presents the challenge of implementation. CFF is prepared to partner with stakeholders to enhance
Mary Dwight, Albert Faro
doaj   +1 more source

An analysis of Pompe newborn screening data: a new prevalence at birth, insight and discussion

Frontiers in Pediatrics
This study includes over 11.6M newborns screened (NBS) for Pompe Disease (PD) from 29 distinct universal screening programs across 8 countries and 4 continents.
R. Colburn, David Lapidus
semanticscholar   +1 more source

Early Postnatal Androgenic Activity Inhibition Produces Differential Long‐Term Alterations in Anxiety‐Like Behavior in Young Adult Male and Female Wistar Rats

Developmental Psychobiology, Volume 68, Issue 6, November 2026.
ABSTRACT Sex differences in anxiety‐like behavior are influenced by gonadal steroids, yet the contribution of early postnatal androgen signaling and testosterone metabolic pathways to the long‐term organization of these behaviors remains unclear. Wistar male and female rats received daily s.c.
Ulises Primo, Jose Manuel Fernández‐García, Rocío García‐Úbeda, Paloma Collado, Beatriz Carrillo, Helena Pinos   +5 more
wiley   +1 more source

Improving newborn screening test performance for metachromatic leukodystrophy: Recommendation from a pre-pilot study that identified a late-infantile case for treatment.

Molecular Genetics and Metabolism
Metachromatic leukodystrophy (MLD) is a devastating rare neurodegenerative disease. Typically, loss of motor and cognitive skills precedes early death.
Teresa H. Y. Wu, Heather A Brown, H. Church, Christopher J. Kershaw, Rebekah Hutton, C. Egerton, James Cooper, K. Tylee, Rebecca Cohen, D. Gokhale, D. Ram, Georgina Morton, Michael J. Henderson, Brian W. Bigger, Simon A. Jones   +14 more
semanticscholar   +1 more source