Results 81 to 90 of about 1,360,274 (268)
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective The aim of this study was to assess how the use of the WHO Child Growth Standards (WHO GS) and the INTERGROWTH‐21st Standards (IG‐21st) affect the classification and interpretation of growth trajectories. Design A secondary data analysis of an observational cohort study.
Linda Vesel +5 more
wiley +1 more source
Expanded Newborn Screening Using Genome Sequencing for Early Actionable Conditions.
Journal of the American Medical Association (JAMA)Importance The feasibility of implementing genome sequencing as an adjunct to traditional newborn screening (NBS) in newborns of different racial and ethnic groups is not well understood.
Alban Ziegler +49 more
semanticscholar +1 more source
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
Allergy, EarlyView.We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
Other title: Use of Quality Initiative to Increase Critical Congenital Heart Defects Screening
, 2015 "To ensure all infants born in Kansas are screened for Critical Congenital Heart Defects (CCHDs). Critical Congenital Heart Defect (CCHD) was added to the Recommended Uniform Screening Panel in September 2011.
core +1 more source
International Journal of Neonatal ScreeningNewborn bloodspot screening (NBS) began in the early 1960s based on the work of Dr. Robert “Bob” Guthrie in Buffalo, NY, USA. His development of a screening test for phenylketonuria on blood absorbed onto a special filter paper and transported to a ...
B. Therrell +7 more
semanticscholar +1 more source
Andrology, EarlyView.ABSTRACT Background As sex chromosome trisomies (SCTs), including 47, XXX, 47, XXY, and 47, XYY, are associated with increased risk for neurodevelopmental challenges, studying SCTs may help in understanding the role of early parental caregiving in shaping neurodevelopmental phenotypes of this genetically at‐risk population.
Sophie van Rijn +4 more
wiley +1 more source
International Journal of Neonatal ScreeningNewborn bloodspot screening (NBS) began in Guthrie’s laboratory in 1961 for phenylketonuria. A federal study the following year formed the basis for expanding NBS as a public health function. Diseases detectable through NBS gradually expanded, eventually
Bradford L. Therrell
doaj +1 more source
European journal of paediatric neurologyINTRODUCTION Metachromatic leukodystrophy (MLD) is a rare autosomal recessive lysosomal storage disorder resulting from arylsulfatase A enzyme deficiency, leading to toxic sulfatide accumulation.
L. Laugwitz +27 more
semanticscholar +1 more source
ANZ Journal of Surgery, EarlyView.Small bowel obstruction in pregnancy is rare but carries high maternal and foetal risk. Across 44 published cases, preterm delivery was 0% after successful conservative management, versus 53% operative and 75% failed conservative. A monitored conservative trial appears feasible in stable, selected patients, with early MRI and a true MDT.
Nesta Emily Baxter +6 more
wiley +1 more source
Newborn Screening for Metachromatic Leukodystrophy: A Systematic Literature Review
International Journal of Neonatal ScreeningA systematic literature review was conducted to evaluate the emerging evidence on newborn screening (NBS) for metachromatic leukodystrophy (MLD; MIM #250100).
L. Laugwitz +5 more
semanticscholar +1 more source