Results 141 to 150 of about 849,858 (379)

Clinical and statistical indicators of the incidence of children born after in vitro fertilization

open access: yesЛечащий Врач
Background. The state of health of children in modern society is changing under the influence of various factors and processes. To a large extent, this applies to children born through in vitro fertilization.
N. P. Provatar   +5 more
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

Spontaneously regressing adrenocortical carcinoma in a newborn. A case report with dna ploidy analysis [PDF]

open access: bronze, 1988
Sonia Saracco   +4 more
openalex   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

open access: yesAdvanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu   +13 more
wiley   +1 more source

Unauthorized Immigrant Population: National and State Trends, 2010 [PDF]

open access: yes, 2011
Analyzes trends in the estimated number of unauthorized immigrants overall, in the workforce, and of newborns with at least one unauthorized-immigrant parent.
D'Vera Cohn, Jeffrey S. Passel
core  

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2010
M. Dominguez-Bello   +6 more
semanticscholar   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

open access: yesAdvanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu   +17 more
wiley   +1 more source

When does right functional hemispheric lateralization arise? Evidence from preterm infants [PDF]

open access: yes, 2009
In recent years, magnetic resonance imaging (MRI) has allowed researchers to individuate an earlier morphological development of the right hemisphere compared to the left hemisphere before birth.
Agnese Suppiej   +2 more
core   +1 more source

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