Results 201 to 210 of about 519,978 (362)

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Optimal Timing for Neonatal Hearing Screening in Well-Babies. [PDF]

Int J Neonatal Screen
Vonk L, van Dommelen P, Eekhout I, Uilenburg NN, Verkerk PH, van der Ploeg CKPB.   +5 more
europepmc   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Developing and validating a neonatal screening tool for congenital anomalies to be used in low- and middle-income country settings. [PDF]

BMJ Glob Health
Gebreselassie HA, Lakhoo K.
europepmc   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

DIFFERENT PATTERNS OF AUTONOMIC HEART RATE CONTROL DURING HYPOXIA IN FETAL AND NEWBORN LAMBS

, 1977
Adrian M. Walker, Jorge B. Cannata‐Andía, Margaret H. Dowling, Bruce Ritchie, J. E. Maloney   +4 more
openalex   +1 more source

Predictive Analytics for Neonatal Health Risk Assessment: A Machine Learning Approach to Early Detection of Critical Health Conditions in Newborns

Agha Wafa Abbas
openalex   +1 more source

INFLUENCE OF GESTATION DATE ON THE SEVERITY OF HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN NEWBORN

, 2023
Ibragimova Nadiya Sabirovna, Diamatova Dinora Norkobil kizi, Rajabov Nodir Ural ugli   +2 more
openalex   +2 more sources

Quantification of glycosaminoglycans in dried blood spots, and evaluation of its usefulness as a secondary newborn screening test for mucopolysaccharidoses. [PDF]

Biochem Biophys Rep
Oboshi W, Hirakiyama A, Miura M, Omachi H, Tanaka M, Seo JH, Ohtake A, Osawa Y, Ishige M, Kosuga M, Munenaga T, Migita O, Nyuzuki H, Sasai H, Fukuda T, Sano S, Ito T, Bo R, Takeshima Y, Esaki H, Inoue T, Nagamitsu S, Watanabe Y, Nakamura K, Sawada H, Maruyama S, Murayama K, Okuyama T.   +27 more
europepmc   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source