Results 241 to 250 of about 849,858 (379)

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Women's Perceptions on Newborn Care Practices, Knowledge Sources, Benefits, and Challenges in Rural Northern Jordan: A Qualitative Study. [PDF]

Healthcare (Basel)
Alrabab'a MH, Maabreh RS, Yehia DB, Eyadat AM, Ashour A, Bani Hani S, Mohammad AA, Alsharairi NA, Alkhsealat Y, Abusbaitan H, Alali WT.   +10 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Newborn [PDF]

Literary Imagination, 2013
openaire   +2 more sources

Elevated Blood Pressure in Newborns From Hypertensive Disorders of Pregnancy During the Immediate Postnatal Period. [PDF]

J Clin Hypertens (Greenwich)
Freel CI, Bavari AE, Mauch TJ, Hanson CK, Mishra PK, Anderson-Berry AL.   +5 more
europepmc   +1 more source

Stratification of Risk of Early-Onset Sepsis in Newborns ≥34 Weeks’ Gestation

Pediatrics, 2014
G. Escobar, K. Puopolo, S. Wi, Benjamin J. Turk, Michael W. Kuzniewicz, Eileen M. Walsh, T. Newman, J. Zupancic, E. Lieberman, D. Draper   +9 more
semanticscholar   +1 more source

“Time Is Brain” – for Cell Therapies

Advanced Science, EarlyView.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin, Dominikus Brian, Rebecca Z. Weber, Patrick D. Lyden, Ruslan Rust   +4 more
wiley   +1 more source

LDL-cholesterol in newborns and children with genetically verified familial hypercholesterolaemia: implications for cholesterol-based screening. [PDF]

Eur Heart J
Bogsrud MP, Stava TT, Berge KE, Strøm TB, Retterstøl K, Holven KB.   +5 more
europepmc   +1 more source

Is meconium from healthy newborns actually sterile?

Research in Microbiology, 2008
E. Jiménez, M. Marín, Rocío Martín, J. M. Odriozola, M. Olivares, J. Xaus, L. Fernández, J. M. Rodríguez   +7 more
semanticscholar   +1 more source