Results 81 to 90 of about 255,153 (264)

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

open access: yesAdvanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang   +18 more
wiley   +1 more source

HIV Infection, Pregnant Women, and Newborns: A Policy Proposal for Information and Testing

open access: yes, 1990
Interest in screening pregnant women and newborns for evidence of HIV infection has increased along with awareness of the public health impact of HIV infection in women and children.

core   +1 more source

Respiratory distress in newborns: current state of the problem

open access: yesВестник анестезиологии и реаниматологии
Introduction. Respiratory distress of newborns is one of the most common causes of complications, irreversible damage to the central nervous system and deaths in the neonatal period.The objective was to analyze the current features of epidemiology, risk ...
D. O. Ivanov   +2 more
doaj   +1 more source

Group B Streptococci Vaginal-Recto Colonization, Vertical Transmission to Newborns, Antimicrobial Susceptibility Profile and Associated Factors in Selected Health Facilities of Bahir Dar City: A Cross-Sectional Study

open access: yesInfection and Drug Resistance, 2021
Yasabe Leykun,1 Chalachew Genet,1 Wondemagegn Mulu1,2 1Department of Medical Laboratory Science, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia; 2Department of Biochemistry and Microbiology, Faculty of Sciences, Ghent ...
Leykun Y, Genet C, Mulu W
doaj  

Peculiarities of health and bone metabolism of children born through IVF

open access: yesМедицинский совет, 2019
The multiple increase in the number of «conceived in vitro» newborns is accompanied by an increase in the number of questions arising around this method of infertility treatment Evaluating the potential health realities of this category of children, it ...
N. A. Druzhinina, D. R. Merzlyakova
doaj   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

open access: yesAdvanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi   +10 more
wiley   +1 more source

Improving maternal and neonatal health: Measuring the impact of the PAIMAN project in ten districts in Pakistan—A Summary: Comparing baseline and endline survey findings (2005-2010) [PDF]

open access: yes, 2010
This is a summary of the Pakistan Initiative for Mothers and Newborns (PAIMAN) project’s endline report. The project interventions fell into two broad areas: 1) health systems upgradation and 2) behavior change communication/community mobilization.
Pakistan Initiative for Mothers and Newborns (PAIMAN)
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren   +5 more
wiley   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

open access: yesAdvanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk   +11 more
wiley   +1 more source

The Tiniest Newborns

open access: yes, 1983
Questions have been raised about the prevailing practice of initiating aggressive therapy for very low birth weight infants. Advocates of conservative care are concerned about the financial burden to society, the quality of life of surviving infants ...
Strong, Carson
core   +1 more source

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