Results 271 to 280 of about 19,456,354 (363)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Compass Rose: Providing Direction and Automation of Glomerular Disease Drug Monitoring. [PDF]

Kidney360
Bobart SA, Aslam N.
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

A dialogue on innovation in anticancer drug discovery. [PDF]

RSC Med Chem
Samajdar S.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

The 2025 KDIGO IgA nephropathy guideline update: an ERA Immunonephrology Working Group perspective. [PDF]

Clin Kidney J
Stamellou E, Bruchfeld A, Caravaca-Fontan F, Frangou E, Kronbichler A, Mirioglu S, Moran SM, Stevens KI, Teng YKO, Steiger S, Floege J.   +10 more
europepmc   +1 more source

The Global Third Nuclear Age: Clashing Vision for a New Era in International Politics

Sana Ahmed
openalex   +1 more source

A New Era in Skincare: The critical role of biosurfactant-producing bacteria in creating biodegradable, non-toxic and skin-friendly cosmetic products [PDF]

K. V. Makwana, A. N. Mehta, Jaynesh K Ambechada   +2 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The New Era of Holistic and Precision Dentistry with Integration of Digital Twin Technology: A Scoping Review. [PDF]

Int J Clin Pediatr Dent
Thribhuvanan L, Saravanakumar MS, Panikkar P, Durairaj P.   +3 more
europepmc   +1 more source