Results 301 to 310 of about 18,189,373 (355)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Newer laboratory indices for identification of metabolic dysfunction-associated steatotic liver disease in obesity. [PDF]

open access: yesJ Family Med Prim Care
Kubendran RA   +6 more
europepmc   +1 more source
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Renal outcomes with the newer antidiabetes drugs: the era before and after CREDENCE

Diabetic Medicine, 2020
AbstractIn 2008, the US Food and Drug Administration provided guidance for the evaluation of the cardiovascular safety of antidiabetes drugs. The newer antidiabetes drugs, approved after 2008, were therefore evaluated in long‐term cardiovascular outcome trials, designed and powered for the assessment of cardiovascular safety.
A. Rajani   +3 more
openaire   +2 more sources

Newer developments in idiopathic pulmonary fibrosis in the era of anti-fibrotic medications

Expert Review of Respiratory Medicine, 2016
Idiopathic pulmonary fibrosis (IPF) is the most common interstitial lung disease with a fatal prognosis. Over the last decade, the concepts in pathobiology of pulmonary fibrosis have shifted from a model of chronic inflammation to dysregulated fibroproliferative repair in genetically predisposed patients.
Girish B, Nair   +3 more
openaire   +2 more sources

Dampak Transformasi Era Digital Terhadap Manajemen Sumber Daya Manusia

Jurnal Bintang Manajemen, 2023
The digital era has changed the paradigm and practice of human resource management (HR). This article analyzes the impact of digital transformation on HR, with a focus on paradigm shifts, digital skills development, and the use of technology in decision ...
A. Wahyudi   +10 more
semanticscholar   +1 more source

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