Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Rediscovering the atrioventricular node artery: anatomical reappraisal of Bonapace's branch. [PDF]
Gupta SK.
europepmc +1 more source
Evolving Management Paradigms in Dural Arteriovenous Fistulas: From Classification to Personalized Endovascular Therapy. [PDF]
Shekar V, Lucke-Wold B.
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The tissue is the issue: Going beyond histopathology in antibody-mediated rejection in heart transplant patients. [PDF]
Mansouri P, Kim PJ.
europepmc +1 more source
Newer laboratory indices for identification of metabolic dysfunction-associated steatotic liver disease in obesity. [PDF]
Kubendran RA +6 more
europepmc +1 more source
Contemporary Use of Implantable Cardioverter-Defibrillators in the Era of 4-Pillar Heart Failure Therapy---an International Survey. [PDF]
Vandenberk B +3 more
europepmc +1 more source
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