Results 41 to 50 of about 3,252,482 (283)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
International news production in post-Soviet Ukraine: Where is the ‘center’? [PDF]
This paper focuses on the geography of news sources and news flows, which are involved in international news production in Ukraine. It seeks answers to the following questions: which sources – Western-based media and global news agencies or their ...
Natalya Ryabinska
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Constitution and Bylaws of The Pioneers of Newport News
This is the image of a small booklet containing the constitution and bylaws of the Pioneers Club of Newport News, Virginia. The Pioneers Club was an association of men who had lived a long period of time in Newport News, Virginia and had made ...
The Pioneers of Newport News
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
While it is generally acknowledged that news agencies play a pivotal role in the current news landscape, empirical insights into the extent of news media’s reliance on agency copy are scarce.
Jelle Boumans +3 more
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Silent Partner: News Agencies and 21st Century news
This article investigates the ubiquitous presence of news agencies (or wire services) in the daily news. While considering the international environment, it focuses on the sole Australian news agency, Australian Associated Press (AAP), and on its ...
Jane Johnston, Susan Forde
doaj

