Results 101 to 110 of about 1,367,422 (277)

AI-Powered Intelligent News Aggregator

open access: yesInternational Journal of Advanced Research in Science, Communication and Technology
In the era of information overload, users face challenges in accessing reliable and timely news from multiple sources. This project presents a News Aggregator System designed to collect, categorize, and present news content from diverse websites in a centralized and user-friendly platform.
null Rohini C, null Dr. V. Vijayakumar
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

La circulation des nouvelles sur l’internet. L’interconnexion médiatique au service du pluralisme ?

open access: yesSur le Journalisme, 2013
L’article consiste en une étude pluri-méthodologique du paysage des actualités en ligne, dans le cadre d’un projet de recherche intitulé Internet Pluralisme et Redondance de l’Information.
Emmanuel Marty, Annelise Touboul
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

How Modern News Aggregators Help Development Communities Shape and Share Knowledge

open access: yesInternational Conference on Software Engineering, 2018
M. Aniche   +6 more
semanticscholar   +1 more source

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