Results 91 to 100 of about 3,444,607 (339)

The Grub-Street Journal and the Changing Culture of Information in the Early 1730s [PDF]

open access: yes, 2012
Between 1730 and 1733, the Grub-Street Journal was one of the most renowned and controversial weekly news-sheets produced and sold in London. This article traces the attempts made by the editors of the Journal to make sense of, and manipulate, the ...
Howard, E
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

News Won’t Find Me? Exploring Inequalities in Social Media News Use With Tracking Data

open access: yesInternational Journal of Communication, 2022
The rise of news content on social media has been accompanied by a hope that people with lower socioeconomic status and less interest in political affairs would be “accidentally” exposed to news.
Lisa Merten   +4 more
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Making News: Balancing Newsworthiness and Privacy in the Age of Algorithms [PDF]

open access: yes, 2016
In deciding privacy lawsuits against media defendants, courts have for decades deferred to the media. They have given it wide berth to determine what is newsworthy and so, what is protected under the First Amendment.
Carroll, Erin C.
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Education in the News and in the Mind

open access: yesNordicom Review, 2013
The Programme for International Student Assessment (PISA) has gained popularity in educational debates, and scholars argue that the tests influence national educational governance.
Fladmoe Audun
doaj   +1 more source

Spaces and Places of News Consumption [PDF]

open access: yes, 2016
If we want to understand much of what makes news use meaningful for people, it is important to accentuate not only what they consume, how and when, but also where. Simply put, the places and spaces of news consumption matter, and matter significantly, for how people choose, interpret, and attend to the news.
openaire   +2 more sources

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