Results 91 to 100 of about 3,444,607 (339)
The Grub-Street Journal and the Changing Culture of Information in the Early 1730s [PDF]
Between 1730 and 1733, the Grub-Street Journal was one of the most renowned and controversial weekly news-sheets produced and sold in London. This article traces the attempts made by the editors of the Journal to make sense of, and manipulate, the ...
Howard, E
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
News Won’t Find Me? Exploring Inequalities in Social Media News Use With Tracking Data
The rise of news content on social media has been accompanied by a hope that people with lower socioeconomic status and less interest in political affairs would be “accidentally” exposed to news.
Lisa Merten +4 more
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Making News: Balancing Newsworthiness and Privacy in the Age of Algorithms [PDF]
In deciding privacy lawsuits against media defendants, courts have for decades deferred to the media. They have given it wide berth to determine what is newsworthy and so, what is protected under the First Amendment.
Carroll, Erin C.
core +2 more sources
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Education in the News and in the Mind
The Programme for International Student Assessment (PISA) has gained popularity in educational debates, and scholars argue that the tests influence national educational governance.
Fladmoe Audun
doaj +1 more source
Spaces and Places of News Consumption [PDF]
If we want to understand much of what makes news use meaningful for people, it is important to accentuate not only what they consume, how and when, but also where. Simply put, the places and spaces of news consumption matter, and matter significantly, for how people choose, interpret, and attend to the news.
openaire +2 more sources

