Results 51 to 60 of about 98,089 (310)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Ethnocentrism in Conflict News Coverage: A Multimodal Framing Analysis of the 2018 Gaza Protests in The Times of Israel and Al Jazeera

open access: yesInternational Journal of Communication, 2021
This study is based on a multimodal content analysis of the news coverage of the 2018 Palestinian protests at Gaza’s borders with Israel. In particular, two regionally based transnational English language news websites were studied, The Times of Israel (
Belal Doufesh, Holger Briel
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Strategic news frames and public policy debates: Press and television news coverage of the euro in the UK

open access: yes
There is growing concern amongst observers of the media that news coverage of politics has moved away from a focus on issues, and instead towards political strategy.
Jackson, Dan
core   +1 more source

Predicting News Coverage of Scientific Articles

open access: yesProceedings of the International AAAI Conference on Web and Social Media, 2018
Journalists act as gatekeepers to the scientific world, controlling what information reaches the public eye and how it is presented. Analyzing the kinds of research that typically receive more media attention is vital to understanding issues such as the “science of science communication” (National Academies of Sciences, Engineering, and
Ansel MacLaughlin   +2 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Superficial, shallow and reactive: How a small state news media covers politics

open access: yesNordicom Review, 2021
This article illustrates how the crisis of the news media is impacting political coverage in Iceland. Perceptions of routine political coverage in the Icelandic media have not been studied before, and this article fills this research gap and situates the
Ólafsson Jón Gunnar
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Strategic Media, Cynical Public? Examining the Contingent Effects of Strategic News Frames on Political Cynicism in the UK

open access: yes, 2010
Through the use of experimental methods, this study examines the claim that strategic news engenders political cynicism. Firstly, it builds upon previous theory by conceptualising and measuring political cynicism at both issue-specific and global levels.
Jackson, Dan, Dan Jackson
core   +1 more source

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