Results 141 to 150 of about 71,839 (318)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
ලිංගික අපරාධ වාර්තාකරණය සහ මාධ්ය ආචාර ධර්ම
, 2018 This entry includes a write-up and an infographic (in Sinhala).During the month of January 2018 several newspapers and tv news telecasts/programmes reported on the sexual assault case of a minor in the Magama area.
Ethics Eye
core
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
දිවි අහිමි කරගැනීම පිළිබඳ වාර්තාකරණ සහ මාධ්ය ආචාර ධර්ම
, 2018 This entry includes 14 write-ups and 14 Infographics (in Sinhala and Tamil).In the month of September 2018, Divaina, Lakbima, Mawbima, Lankadeepa, Virakesari and Thinakkural reported suicides without including suicide helplines while including method of ...
Ethics Eye
core
සියදිවි හානිකරගැනීම් පිළිබඳ පුවත් වාර්තාකරණය: කෙතරම් දුරට සදාචාරාත්මකද?
, 2020 This entry includes 15 write-ups and 16 infographics. (all in Sinhala)In November 2020, several newspapers (Aruna. Lankadeepa, Mawbima, Dinamina, Divaina) and news telecasts of TV channels (Hiru, Derana, ITN, Swarnavahini) reported news on suicide ...
Ethics Eye
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source