Results 31 to 40 of about 12,447 (266)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Ideologi Media dan Framing Pada Pemberitaan Perusakan Rumah Ibadah di Kompas dan Republika

Jurnal Peurawi: Media Kajian Komunikasi Islam, 2021
This study aims to find out how the framing in the news related to the destruction of the Musala in North Minahasa on the news of online  media Kompas.com in the period 30 January to 13 February 2020 and Republika.co.id for the period 30 January 2020 to ...
Farid Muthaqin, Hamdani M Syam, Putri Wahyuni   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Framing government during COVID-19 pandemic: comparing Sino-US newspapers in issue attention cycle and hierarchical government representation

Humanities & Social Sciences Communications
Despite growing cross-national studies on pandemic news and government representation, less is known about government news framing with longitudinal, cross-national, and hierarchical government (national vs. local) comparisons.
Xiaojing Li, Xiangping Tan
doaj   +1 more source

Nostalgia waves: a media framing of post-Communist nostalgia in Romania [PDF]

Polis: Revista de Stiinte Politice, 2020
This article explores the post-communist nostalgia waves within a media framing perspective, focusing first on the context of the 20th anniversary of the fall of the Romanian communist regime, when public opinion polls, along with their media coverage ...
Alexandra BARDAN
doaj  

A retrospective study exploring how South African newspapers framed Schizophrenia and other psychotic disorders over an 11-year period (2004–2014)

BMC Psychiatry, 2022
Background: The way schizophrenia is portrayed in the media contributes to the dissemination of misinformation about the symptoms, causes, and treatment of mental disorders and has the potential to perpetuate or mitigate the stigmatization of ...
Nombuso Masinga, Patrick Nyamaruze, Olagoke Akintola   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

PEMBINGKAIAN GAMBAR BERITA DI METROTV DAN RCTI MENJELANG PILKADA DKI JAKARTA 2017

Capture, 2017
Framing images is one way used by MetroTV and RCTI in proclaiming Elections of DKI Jakarta. The goal is to build the public opinion.This study was conducted to find out the news ahead of Jakarta elections framed by Metro TV and RCTI.This research uses ...
Ulfa Aci Zairiyah, Achmad Sjafi'i
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source