Results 81 to 90 of about 2,169,062 (297)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This item contains two issues of the Take One newsletter: October 11, and 25, 1984Take One was published every two weeks and focused on short news items and announcements "for the people of University Hospital.
core
Detecting frames in news headlines and its application to analyzing news framing trends surrounding U.S. gun violence [PDF]
Different news articles about the same topic often offer a variety of perspectives: an article written about gun violence might emphasize gun control, while another might promote 2nd Amendment rights, and yet a third might focus on mental health issues ...
Betke, Margrit +4 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Climate news mediates extreme weather effects on climate change concern
As the severe impacts of climate change become increasingly apparent, concerns about climate-related issues have grown in recent years. The news media plays an important role in disseminating information about climate change and its consequences to the ...
Jonas Peisker +2 more
doaj +1 more source
Take one: September 1984 [PDF]
This item contains two issues of the Take One newsletter: September 13, and 27, 1984Take One was published every two weeks and focused on short news items and announcements "for the people of University Hospital.
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Identifying Emerging Issues in the Seafood Industry Based on a Text Mining Approach
Identification of emerging issues has garnered growing interest as a way to establish proactive policy formulation. However, in fisheries research, analyzing such issues has largely depended on the literature or researchers’ judgment.
Kiuk Han, Jaesun Yeom, Keunsuk Chung
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
This item contains two issues of the Take One newsletter: November 8, and 22, 1984Take One was published every two weeks and focused on short news items and announcements "for the people of University Hospital.
core

