Results 101 to 110 of about 1,558,961 (274)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
From Page to Stage to Screen and Beyond [PDF]
, 2012 A group of Chicago youth media organizations have embarked on an evaluation process with adult program alumni to assess the degree to which hands-on media production and dissemination contributes to developing productive, independent, and engaged ...
Amy Terpstra, Suniya Farooqui
core
Duality in Semi-Exclusive Processes
, 2002 Bloom-Gilman duality relates parton distributions to nucleon form factors and thus constrains the dynamics of exclusive processes. The quark electric charge dependence implies that exclusive scattering is incoherent on the quarks even at high momentum ...
Hoyer, Paul
core +2 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A Systematic Literature Review on Local News Production (2012–2022)
Comunicação e SociedadeLocal media are a cornerstone of communities, providing helpful information for everyday life, but the news production has undergone massive changes as a result of digital technologies.
Rubén Rivas-de-Roca +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Non-Western coverage of local crises in the societal-security perspective
RUDN journal of SociologyThe article considers a small segment of the non-Western-centric world to understand how a selection of Bangladeshi news media covers the Russia-Ukraine conflict, i.e., the authors focus on the mass media coverage rather than how the Bangladeshi ...
A. K. Khan, A. Hossain, A. N. Shazed
doaj +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source