Results 111 to 120 of about 1,558,961 (274)

The Agency Makes the (Online) News World go Round: The Impact of News Agency Content on Print and Online News

open access: yesInternational Journal of Communication, 2018
While it is generally acknowledged that news agencies play a pivotal role in the current news landscape, empirical insights into the extent of news media’s reliance on agency copy are scarce.
Jelle Boumans   +3 more
doaj   +2 more sources

International news production in post-Soviet Ukraine: Where is the ‘center’? [PDF]

open access: yesGlobal Media Journal: German Edition, 2012
This paper focuses on the geography of news sources and news flows, which are involved in international news production in Ukraine. It seeks answers to the following questions: which sources – Western-based media and global news agencies or their ...
Natalya Ryabinska
doaj  

Truth, Lies, and Copyright [PDF]

open access: yes, 2019
Fake news may be trending right now, but fake news is not the only source of fake facts that we consume. We encounter fake facts every day in the historical or biographical books we read, the movies we watch, the maps we study, the tele-phone directories
Smith, Cathay Y. N.
core   +3 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Game Theoretic Analysis of Ideologically Biased Clickbait or Fake News, and Real News

open access: yesOperations Research and Decisions, 2020
A decision and game theoretic model is developed for how one and two news organisations strike balances between producing clickbait or fake news, and real news. Each news organisation seeks to attract gullible consumers who consume more clickbait or fake
Kjell Hausken
doaj  

Algorithms and Architecture for Real-time Recommendations at News UK

open access: yes, 2017
Recommendation systems are recognised as being hugely important in industry, and the area is now well understood. At News UK, there is a requirement to be able to quickly generate recommendations for users on news items as they are published.
Bailey, Dion   +3 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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